Not exact matches
Haslam SZ, Shyamala G. Progesterone
receptors in normal mammary glands of
mice: characterization and relationship to development.
Oxytocin
receptor in the Hypothalamus is Sufficient to Resue Normal Thermoregulation Function in Male Oxytocin Receptor Knocko
receptor in the Hypothalamus is Sufficient to Resue
Normal Thermoregulation Function
in Male Oxytocin
Receptor Knocko
Receptor Knockout
Mice.
For this study the researchers targeted very specific types of GABA
receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA
receptors and actually reduce the ability to socially interact
in normal mice — underscoring that future medications would need to target very specific
receptors so as not to diminish the drug's impacts.
Researchers led by Emory University pathologist Andrew Gewirtz found that
mice genetically deficient
in an immune system
receptor have altered gut bacteria, eat more than
normal mice do, and develop features of metabolic syndrome.
But
mice dads that lacked this
receptor in the epididymis had offspring with
normal hormonal responses.
Although the Nppb - knockout
mice lived a
normal lifespan, when the researchers killed the
receptor cells
in the spinal cord, the
mice died prematurely, suggesting that it could be dangerous to try humans, Hoon says.
Longo also knew of research by molecular biologist John Kopchick at Ohio University, which showed that
mice with a mutation
in their growth hormone
receptor gene lived 40 percent longer than
normal mice — the equivalent of an average American living to age 110.
To solve this mystery, the scientists generated
mice with
normal or reduced levels of A2A
receptors in astrocytes and compared them on tests of learning and memory.
In normal - weight
mice, activation of this
receptor decreases orexin A release.
The scientists found that transgenic
mice in which phospholipase Cγ1 was unlinked from the TrkB
receptor were less susceptible to seizures than
normal mice.
Jetlagged
mice lacking a
receptor called FXR, which keeps bile acid level
in the liver within a
normal physiological range, had higher bile acid levels and much more liver cancer.
Teh, H.S., Kishi, H. & von Boehmer, H. Deletion of autospecific T cells
in T cell
receptor (TCR) transgenic
mice spares cells with
normal TCR levels and low levels of CD8 molecules.
Winkler, E. A., Bell, R. D. & Zlokovic, B. V. Pericyte - specific expression of PDGF beta
receptor in mouse models with
normal and deficient PDGF beta
receptor signaling.
One important difference: the Doogie
mice had all their
normal genes, and were overproducing a NMDA
receptor gene involved
in helping neurons communicate.
Skeletal analysis of the
mice deficient
in MT1 or MT2 melatonin
receptors showed a low bone mass
in MT2 - / -
mice while MT1 - / -
mice had a
normal bone mass compared to the WT
mice.
The researchers also showed that regular feeding with the Lactobacillus strain caused changes
in the expression of
receptors for the neurotransmitter GABA
in the
mouse brain, which is the first time that it has been demonstrated that potential probiotics have a direct effect on brain chemistry
in normal situations.