Sentences with phrase «receptor polymorphisms»

Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin - 4 receptor polymorphisms.

Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin - 4 receptor polymorphisms identified in obese humans.

Uhm — And in terms of — you know — you see the VDR in here, which is Vitamin D Receptor Polymorphisms.

Based on past research suggesting that BMI associations with dopamine receptor polymorphisms are due to increased food craving [36, 38], we expected that BMI would be related to dopamine receptor genotype.

Melanocortin - 1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?

This study examined whether adolescent conduct disorder and adult antisocial behavior were related to the dopamine D2 receptor polymorphism (DRD2) and the dopamine D4 receptor polymorphism (DRD4).

Cultural consonance, a 5HT2A receptor polymorphism, and depressive symptoms: a longitudinal study of gene × culture interaction in urban Brazil

Experimental evidence for differential susceptibility: Dopamine D4 receptor polymorphism (DRD4 VNTR) moderates intervention effects on toddler» externalizing behavior in a randomized controlled trial

The VIPP - SD proved to be especially effective in decreasing externalizing behavior in children with the Dopamine D4 receptor polymorphism, a polymorphism that is associated with motivational and reward mechanisms and Attention Deficit Hyperactivity Disorder in children (Bakermans - Kranenburg et al. 2003).

Not exact matches

A polymorphism (rs1051730) in proximity to the cholinergic receptor, nicotinic, alpha 3 (CHRNA3) gene is associated with higher tobacco consumption among smokers and can therefore be used as a genetic proxy for high tobacco consumption.

This study further investigated the impact of nicotine use / smoking status and variation in the mu opioid receptor gene (OPRM1), specifically, an A118G single nucleotide polymorphism (SNP, or DNA sequence variation), on the effects of naltrexone on a range of drinking outcomes.

The nucleotide - binding oligomerization domain - containing protein 1 (NOD1) polymorphism S7N does not affect receptor function.

Polymorphisms of the scavenger receptor class B member 1 are associated with insulin resistance with evidence of gene by sex interaction

The impact of common dopamine D2 receptor gene polymorphisms on D2 / 3 receptor availability: C957T as a key determinant in putamen and ventral striatum.

Pro12Ala polymorphism in the peroxisome proliferator - activated receptor - γ2 (PPARγ2) is associated with higher levels of total cholesterol and LDL - cholesterol in male caucasian type 2 diabetes patients

The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5 - HT2A and serotonin transporter linked polymorphic region -5-HTTLPR - of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E... (ApoE) and between themselves, in a sample of 208 sporadic AD patients and 116 normal controls from Italy.

Sex - specific differences in the ANKK1 (rs1800497) polymorphism of dopamine receptor D2 in humans were reported with increased risk for T2DM in women, which could not be found in men (193).

The aim of this study was to investigate the role of serotonin in depression, searching for association of two serotoninergic polymorphisms (T102C of serotonin receptor 5 - HT2A and serotonin transporter linked polymorphic region -5-HTTLPR - of SLC6A4 gene) with depressive symptoms and considering their possible interactions with Apolipoprotein E

Vitamin D receptor gene polymorphisms, serum 25 - hydroxyvitamin D levels, and melanoma: UK case - control comparisons and a meta - analysis of published VDR data.

A new study — the first to focus on the 120/240 polymorphism — adds to the literature implicating the dopamine receptor in ADHD.

As they pointed out, the repeat occurs in a region of DRD4 associated with gene activity, so the 120/240 polymorphism may have a functional effect on the dopamine receptor.

After a chance discovery, another polymorphism in the dopamine D4 receptor gene is linked to attention deficit hyperactivity disorder

«Looking for reward in all the wrong places: dopamine receptor gene polymorphisms indirectly affect aggression through sensation - seeking.»

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

Polymorphisms in five of 15 genes (33 %) encoding molecules known to primarily influence pancreatic beta - cell function - ABCC8 (sulphonylurea receptor), KCNJ11 (KIR6.2), SLC2A2 (GLUT2), HNF4A (HNF4alpha), and INS (insulin)- significantly altered disease risk, and in three genes, the risk allele, haplotype, or both had a biologically consistent effect on a relevant physiological trait in the QT study.

Duffy blood group polymorphisms are important in areas where Plasmodium vivax predominates, because this molecule acts as a receptor for this protozoan.

Here we examine the relationships between genetic polymorphisms of dopamine receptor genes and several phenotypes in Ariaal men.

This study analyzes the correlates of two genetic polymorphisms, the TaqI A polymorphism in the dopamine receptor D2 (DRD2) gene and the 48 base pair (bp) repeat polymorphism in the dopamine receptor D4 (DRD4) gene.

Adequate levels are complicated by genetic factors, as the Vitamin D Receptor (VDR) polymorphism is relatively common.

Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption

: To investigate whether the +1730 G / A polymorphism in the estrogen receptor (ER)- beta gene is associated with susceptibility to polycystic ovary syndrome (PCOS).

(6) Genetic studies show polymorphism or genetic mutations in the Estrogen receptors.

A lot of people with Hashimoto's and hypothyroid autoimmune issues tend to have a vitamin D polymorphism at the receptor site of the vitamin D receptor and they need higher levels of vitamin D, 70 to a hundred.

Cornelis MC, El - Sohemy A, Campos H. Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption.

Abstract: Both D4 dopamine receptor (DRD4) exon 3 and tyrosine hydroxylase (TH) intron 4 repeat polymorphisms have been linked to activity and impulsivity in German Shepherd Dogs (GSDs).

Androgen receptor gene polymorphisms are associated with aggression in Japanese Akita Inu.

The toll - like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis.

The study suggests that oxytocin receptor gene polymorphisms have an impact on proximity to unfamiliar humans and on how friendly the dogs were toward the human.

This is the first study to suggest that dog sociality toward people is related to polymorphisms in the OXTR (oxytocin receptor) gene.

A factor analysis based on descriptors of 81 Labrador retrievers being trained as guide dogs found that polymorphisms in two genes — comt and the glutamate receptor (slc1a2)-- significantly related to a principal component described as «activity».

Dopamine D4 receptor (DRD4) gene polymorphism is associated with attachment disorganization in infants

This investigation examined the extent to which polymorphisms of the serotonin transporter linked promoter region (5 - HTTLPR) and the dopamine receptor D4 (DRD4) genes differentially influenced the development of attachment security and disorganization in maltreated and nonmaltreated infants at age 13 months, and the extent to which the efficacy of preventive interventions to promote attachment security were influenced by genetic variation.

Dopamine D4 receptor exon III polymorphism, adverse life events and personality traits in a nonclinical German adult sample

Association analysis of the catechol - o - methyltransferase (COMT), serotonin transporter (5 - HTT) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive - compulsive disorder

Characterization of a glucocorticoid receptor gene (GR, NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance

Glucocorticoid Receptor (NR3C1) Gene Polymorphism Moderate Intervention Effects on the Developmental Trajectory of African - American Adolescent Alcohol Abuse.

The effects of child maltreatment and polymorphisms of the serotonin transporter and dopamine D4 receptor genes and infant attachment and intervention efficacy

Socioeconomic status mediates the genetic contribution of the dopamine receptor D4 and serotonin transporter linked promoter region repeat polymorphisms to externalization in preadolescence

Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: Results from a high - risk community sample

Association between dopamine D4 receptor (DRD4) exon III polymorphism and neuroticism in the Japanese population