And when lectins take up residence on insulin
receptors on nerve cells, your neurons never get the energy that they need, and so they continually send a message that you're hungry in hopes of getting more fuel.
The nanoparticle's shape gives it more surface area than spherical particles, improving the surface protein's ability to bind with
receptors on nerve cells that serve as a gateway to the nervous system.
Now, researchers have determined that an unstable chemical in crushed, raw garlic titillates two
receptors on nerve cells that trigger pain — the same receptors that are stung by hot peppers and menthol.
The social environment seems to affect
the receptors on nerve cells that respond to neurotransmitters like serotonin, which in turn changes how alcohol affects nerves.
Maged Harraz, Ph.D., a research associate and the first author of the newly published research paper, says the researchers already knew that ketamine interacts with excitatory NMDA
receptors on nerve cells in the brain to block their activity.
Not exact matches
He then administered a compound that helps to facilitate activity by
receptors that sit
on nerve cells and direct the
cells» responses to GABA, and the abnormality was reversed.
The scientists observed that transmission of chemical signals between the
nerve cells are facilitated by AMPA -
receptors and the activity occurs
on the brain
cell surface.
In the current study, Frank Longo, MD, PhD, and others at Stanford University, tested LM22A - 4, a drug that specifically binds to and activates the BDNF
receptor TrkB
on nerve cells, in mice that model the disorder.
«What we think happens is that the bacteria activate immune
cells, which release chemicals called cytokines that then act
on receptors on the sensory
nerves to increase their activity,» he says.
In a report
on the study, published Feb. 5 in Nature Neuroscience, researchers say the biochemical
receptor, known as a G protein - coupled
receptor, was present
on nerve cells in the lower respiratory tracts of lab mice.
Using fluorescent antibodies designed specifically to light up the
receptor in mice, the investigators observed it
on vagus
nerves, which serve as a main biochemical connection between airway
cells and the brain.
«Our data clearly showed that one of the protein
receptors on white blood
cells called CXCR3 brings white blood
cells to the optic
nerve in response to production of its binding partner CXCL10 by damaged
nerve tissue,» said Zhang.
Yonju Ha, a lead author of this article, said that further studies
on this
receptor and its role in white blood
cell recruitment following tissue injury may aid in the development of new interventions for diseases associated with
nerve injury, such as TON, stroke, diabetic retinopathy and glaucoma.
The odorant
receptor molecules sit
on the surface of sensory
nerve cells in our nose.
When chemical phosphate groups are added to the
receptors, they move from the cytoplasm and cluster
on the edges of
nerve cells along synapses — the spaces between
nerve cells where messages transmit from one
cell to another.
a) The Eye in your Thigh: a patch of skin
cells on the leg that can distinguish between bright and dark conditions, perhaps to help regulate the body clock b) The Ear in your Rear:
nerves in the buttocks attuned to infrasound vibrations of between 10 and 25 hertz, perhaps to warn of approaching predators or thunderstorms c) The Nose in your Toes: scent - detecting sebaceous glands
on the feet whose purpose is unclear d) The Tongue in your Lung: taste - bud - like
receptors that detect bitter substances and dilate or restrict the airways accordingly
The impulses cause glutamate (one of the brain's main neurotransmitters) to pop out of one
nerve cell and travel across the synapse to activate the next by binding to its
receptors, chemically active signaling stations
on the
cell surface.
These designer proteins bind tightly to CGRP molecules or their
receptors on trigeminal
nerve cells, preventing
cell activation.
In a brain slice, Olivia Masseck measures the activity of
nerve cells in which she switches
on their
receptors using light stimulation.
As a result, they are too broad: They affect more than one type of
receptor,
on more than one kind of
nerve cell, in more than one part of the brain.
Both endorphins and opioids latch
on to proteins called opioid
receptors on the surface of
nerve cells.
The 5 - HT released by type III
cells could also activate 5 - HT3
receptors on afferent
nerve fibers.
However, a paucity of information exists
on the steps between taste
receptor cell activation and afferent
nerve fiber firing.
Herein, we test whether 5 - HT released by taste
cells plays a role in the transmission of taste information by activation of 5 - HT3
receptors on afferent
nerve fibers.
Those naturally produced opioids, and the opioid drugs that imitate them, inhibit pain by acting
on three kinds of opioid
receptors — mu, kappa and delta — that are found
on the outside of
nerve cells in the brain, spinal cord, digestive tract and elsewhere.
Although Wnts were better known because of their role as morphogens — proteins that pattern bodily structures and determine
cell fates — Zou recently showed how members of the Wnt family served to guide pathfinding axons up and down the spinal cord by attracting or repelling
receptors on the growth cones of sensory or motor
nerves.
They include Fridolin Sulser, who helped develop tricyclic antidepressants, Elaine Sanders - Bush, whose lab made several important discoveries about the neurotransmitter serotonin and its
receptors, and Randy Blakely, nationally known for his work
on transporters, which sweep up neurotransmitter from the synaptic gap between
nerve cells.