This group of about 800
receptors plays a central role in transferring signals from the environment into the cell and is of great interest for drug development.
Not exact matches
The Janus tyrosine kinases (Jaks)
play a
central role in signaling through cytokine
receptors.
They found that elevated anxious temperament is associated with decreased messenger RNA expression of two neuropeptide Y
receptors, Y1R and Y5R, in the
central nucleus of the amygdala, a region of the brain that
plays an important role in regulating fear and anxiety.
A
receptor is a molecule placed on the cell membrane which, in some cases, can direct material from the surroundings to be taken up by the cell and degraded, In the degradation of bone tissue, the
receptor uPARAP
plays a
central role.
• D3 dopamine
receptor, which
plays a vital role in the
central nervous system, affecting our movement, cognition and emotion.
It is commonly argued that cholinergic
receptors do not respond rapidly enough to be involved in generating theta waves, and therefore that GABAergic and / or glutamatergic signals (Ujfalussy and Kiss, 2006) must
play the
central role.
These
receptors are found throughout the
central nervous systems of humans and non-human animals, and
play an important role in pain pathways.
AMANTADINE This drug acts to modulate the pain response by antagonizing the N - methyl - d - aspartate (NMDA)
receptor and the role they
play in
central neuronal hyperexcitability (wind up).