Sentences with phrase «recessive mode of inheritance»

Our pedigree analysis included Swedish vallhund dogs examined in seven different countries, spanning three continents, and was highly suggestive of a genetic etiology and an autosomal recessive mode of inheritance.

To date, researchers at UC Davis School of Veterinary Medicine and the Veterinary Genetics Laboratory have determined that «a recessive mode of inheritance in Haflingers explains some of the genetic components involved in the development of this cancer.

EIC is a hereditary condition with an autosomal recessive mode of inheritance.

L -2-HGA is now known to be transmitted by means of an autosomal recessive mode of inheritance.

A recessive mode of inheritance has been suggested for congenital cataracts and microphthalmia in the Miniature Schnauzer [112] as well as cataracts in the Entlebucher mountain dog [113], the Bichon Frise [114] and the American Cocker spaniel [115].

JME is an inherited defect only in Rhodesian Ridgebacks; it is from a recessive mode of inheritance which means an Affected dog would have inherited two copies of the mutation - one from each parent.

An autosomal recessive mode of inheritance has been postulated and all affected individuals to date are direct descendants of one outstanding living American stud.

All affected dogs were homozygous at these SNP loci, suggesting a recessive mode of inheritance.

Many hereditary conditions have either a recessive mode of inheritance or are polygenic, meaning they are controlled by many genes.

Pedigree examination revealed several features supporting an autosomal recessive mode of inheritance.

The estimated segregation ratio is not consistent with a fully penetrant simple autosomal recessive mode of inheritance.

Analysis of pedigrees from 4005 Bernese mountain dogs with 50 affected dogs revealed a polygenic, recessive mode of inheritance with a predisposition for males 7.

Pidduck et al., (3) working with toy poodles, proposed a simple (autosomal) recessive mode of inheritance.

Dramatic, complete and immediate removal of carriers from a closed / highly related population such as Italian Greyhound's would definitely not be recommended if we were certain of an Autosomal Recessive mode of inheritance.

Research at the University of Helsinki identified the causative gene in 2007, showing an autosomal recessive mode of inheritance.

Not exact matches

The results can be filtered by quality, mode of inheritance (e.g. autosomal, homozygous recessive, compound heterozygous, etc.), population frequencies and known and expected pathogenicity according to ClinVar database and several predictors.

The evidence was in support of a simple autosomal recessive in that breed and it is not improbable that the same mode of inheritance occurs in other breeds.

Although the mode of inheritance is recessive, male dogs born from a carrier female require just one copy of the mutation, the other gene linked to the X chromosome from which disease gets its name.

The German Shepherd Dog and Rough - Coated Collie are particularly at risk and the mode of inheritance appears to be autosomal recessive (meaning genetic carriers will appear normal).

Discovery of genetic links and of the mode of inheritance (simple or complex, dominant or recessive) is the work of researchers, but they must have dogs to study.

Various modes of inheritance of epilepsy have been deduced in different breeds, including simple autosomal recessive 3 with a sex - modifier 4, 5, polygenic recessive 6 with a sex - predilection 7, polygenic with a large contribution by a single autosomal recessive gene 8, and a multi-locus model 9.

Epilepsy in beagles was thought to be homologous to Lafora's disease in man based on the similar findings from histopathological examination 23 and the mode of inheritance was described as autosomal recessive with a sex - linked «suppressor» 4, 5.

The mode of inheritance has not been determined precisely but the fact that dogs heterozygous for the KRT71 mutation do not have curls and also the occasional occurrence of dogs with curly hair in breeds with typically straight hair suggests that the curly hair is inherited in a recessive or incompletely dominant mode.

As stated by Dr. Rubin, it has been assumed that the mode of inheritance is recessive (both parents are carriers), and affected animals are not to be considered to have normal eyes.

If the mode of inheritance for the disease is recessive, yes you can.

The mode of inheritance is not known, although autosomal recessive inheritance is likely; there are no gene - based tests available.

While it is likely to be autosomal recessive, not all dogs fit this mode of inheritance.

In contrast, an autosomal dominant mode of inheritance with a high degree of penetrance has been suggested for the pulverulent (dust - like) form of cataract observed in the Norwegian Buhund [116] and autosomal dominant with variable penetrance has been suggested for inherited posterior polar subcapsular cataracts in the Labrador and Golden retriever [117], although current anecdotal evidence indicates that in the Labrador cataracts could also be inherited as an autosomal recessive trait.

The mode of inheritance is as an «autosomal recessive.»

Renal dysplasia is thought to be a simple recessive problem in shih tzus (Bruyette, Veterinary Information Network (www.vin.com), 1996) but I couldn't find specific information on mode of inheritance in bichons for this condition, either.

The mode of inheritance has been determined to possibly be, autosomal recessive in Keeshonds16, polygenic with one gene of major influence in Belgian Tervurens17, and polygenic recessive in Golden Retrievers.18 Once the mode of inheritance is determined within a breed, we will determine the best technique to try and find a genetic marker linked to epilepsy gene (s) in each breed.

In our study of primary epilepsy, in English Springer Spaniels, Vizslas, and research Beagles the first step will be to determine the mode of inheritance for each breed (simple recessive, simple dominant, sex - linked, or polygenic).

Depending on the particular variety, the mode of inheritance could be autosomal recessive or dominant, or X-chromosome-linked recessive or dominant, some with full penetrance, and some not.

The mode of inheritance for this condition for many years now has been characterized as autosomal recessive meaning that affected dogs have inherited the mutant gene from both parents.

While variability in the age of disease onset and incomplete pedigree information preclude us from drawing any definitive conclusions about the mode of inheritance, the available data is most consistent with an autosomal recessive pattern.