Sentences with phrase «recognize transplanted cells»
As the immune cells in the recipient recognize transplanted cells as foreign, they mount an inflammatory response that can lead to the body rejecting the transplant.
https://www.sciencedaily.com/ Not exact matches
The immune system recognizes transplanted organs as foreign tissue by telltale proteins, called the major histocompatibility complex (MHC), that coat cell surfaces.
Results from a clinical trial investigating a new T cell receptor (TCR) therapy that uses a person's own immune system to recognize and destroy cancer cells demonstrated a clinical response in 80 percent of multiple myeloma patients with advanced disease after undergoing autologous stem cell transplants (ASCT).
Without these cells, the immune system recognizes a newly transplanted lung as harmful and mounts an attack that eventually can lead to rejection of the organ.
Some scientists suspect that immune cells activated by the foreign organ but lacking the CD154 signal die soon after a transplant, although it's not clear why new generations of immune cells wouldn't recognize and attack the tissue.
The mice with transplanted human cells also learned to find their way through a maze in about half the time and were better able to recognize familiar objects in new locations.