Sentences with phrase «recognized by antibodies»

Furthermore, using a phospho - tyrosine [Y] 474 (in - house generated) and a phospho - serine [S] 176 (Cell Signaling, Inc., Danvers, MA) RIPK2 antibodies, we confirmed that active RIPK2 is recognized by these antibodies upon activation with MDP treatment in 293HEK fibroblast and HCT116 colon cancer epithelial cells (Fig. 3E, left panel) and detection of constitutively active RIPK2 in the colon cancer cell line SW480 (Fig. 3E, right panel).

«We identified parasite proteins that are only recognized by antibodies in children who were resistant to malaria, but not by antibodies in susceptible children.»

Using molecular gymnastics, we identified parasite proteins that are only recognized by antibodies in children who were resistant to malaria but not by antibodies in susceptible children.

To validate the screen, the team tagged several of their favorite clock proteins with a short protein tag that's easily recognized by antibodies.

«Prion proteins with a trimmed version of the flexible tail can, however, no longer damage the brain cells, even if their switch has been recognized by antibodies,» explains Adriano Aguzzi.

It used blood samples from individuals with celiac disease to see whether the proteins in gluten - free beer and gluten - removed beer were recognized by antibodies that were already present in the blood.

Not exact matches

Autoimmunity is commonly caused by bacterial infections or overgrowth in the small intestine, in which partially digested food compounds are incorporated into bacterial cell walls and then the immune system, reacting to the bacteria, forms antibodies that also recognize food compounds, some of which might cross-react with human counterparts.

The researchers identified 5 toxins within the snake venom and used a technique called SPOT - synthesis to identify the sections of the toxin (epitopes) that are recognized by coral snake antivenom antibodies.

CIEP and similar immunological methods «are based on detecting proteins by using antibodies that would recognize the protein by shape.

The findings highlight a novel way to generate antibodies that recognize and target proteins shared by most influenza A strains rather than those unique to each strain.

Antibodies are produced by B cells to recognize and defend against viruses.

Antibodies are proteins made by the immune system that recognize foreign viruses and bacteria.

The development of trispecific multivalent antibodies combine the best attributes of each into a single molecule capable of recognizing and neutralizing multiple viruses not recognized by the individual bnAbs.

Another study, led by researchers at NIAID, to be presented at the vaccine conference this week analysed the molecular structure of antibodies from the blood of vaccinated people and found that some of their antibodies recognized the same amino acids in the V2 region.

Just as cells of the immune system use antibodies to recognize pathogens, researchers in this study designed antibodies to recognize a protein over-expressed by these cancer cells, namely the protein mesothelin.

Tier 2 NAbs recognized conformational epitopes that differed between animals and in some cases overlapped with those recognized by broadly neutralizing antibodies (bNAbs), whereas tier 1 responses targeted linear V3 epitopes.

Some of the anti-influenza antibodies generated by the technique recognized multiple strains of the virus and were able to neutralize its ability to infect cells.

Hu14.18 K332A is a laboratory - produced antibody designed to activate the immune response against tumor cells by recognizing and binding to an antigen found on the surface of most neuroblastoma tumor cells.

«HIV is a particularly nasty virus because it's learned how to avoid being recognized, being seen by antibodies,» said Burton.

«One impressive feature about this molecular slingshot,» says Francesco Ricci, Associate Professor of Chemistry at the University of Rome Tor Vergata, «is that it can only be triggered by the specific antibody recognizing the anchoring tags of the DNA «rubber band».

While much recent research has not been published in this area, there is actually a long history of studies that show: (1) there is a significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against cancer can be generated by vaccinating animals with embryonic tissues.

Enzymatic actions of Pasteurella multocida toxin detected by monoclonal antibodies recognizing the deamidated α subunit of the heterotrimeric GTPase Gq.

This new marker of senescent cells is recognized by a naturally occurring IgM antibody that belongs to the innate immune system and is likely to be involved in a natural mechanism of immune recognition and clearance of senescent cells.

The monoclonal biotinylated W0 - 2 (EMI Millipore, USA) recognizing the Aβ N - terminus was used as detection antibody, and the reaction was developed by streptavidin - horseradish peroxidase conjugate and the chromogenic substrate 1 - Step Ultra-TMB (Pierce, USA).

These T cells already recognize the mutant p53 cancer cells, and the vaccine leads to the production of antibodies that flag the cancer for new T cells created by the immune system.

By Day 42, immunized animals generated plasma Abeta antibodies that labeled Abeta plaques in human, AD transgenic mouse and vervet brains; bound Abeta1 - 7; and recognized monomeric and oligomeric Abeta but not full - length amyloid precursor protein nor its C - terminal fragments.

Using antibodies against the tetraspannin CD9 and the pericellular matrix proteoglycan recognized by monoclonal antibody GCTM - 2 [14], we fractionated HES - 2, HES - 3 and H9 cells grown on serum - containing medium or in the presence of Knockout serum replacer and FGF - 2 respectively.

Antibody a protein produced naturally by the immune system to recognize and neutralize foreign substances.

To demonstrate that serum antibodies were recognizing conformational epitopes within the protein library, all recombinant proteins were denatured by heat treatment before being captured via their biotin tag.

The thyroid antibodies indicate that the thyroid gland has been recognized as a foreign invader by the immune system and that the thyroid gland is under attack.

HOW VACCINES WORK After vaccination, the immune system is «trained» to recognize infectious agents by producing proteins called antibodies or activating specific cells to kill the agents.

Diagnosis of Rocky Mountain spotted fever is best made by recognizing the clinical signs, in conjunction with blood antibody testing to document recent exposure and infection.