Sentences with phrase «recognized by the immune system»

The gluten in grain is not recognized by the immune system, so it attacks the intestines and can cause severe damage.

The components of this vaccine would be short flu virus fragments — called epitopes — that are already known to be recognized by the immune system.

By examining blood plasma of two - year - olds exposed to the disease, researchers have discovered a new vaccine target: a protein recognized by the immune systems of malaria - resistant children.

They also found that mutations in the cassettes that could affect the portion of VlsE that is recognized by the immune system were as much as eight times more common than would be expected by chance alone and more common than mutations that affected other parts of the VlsE protein.

The basic problem the team faced with these and other vaccines they've developed is that the opioid drugs are small molecules, which are not recognized by the immune system.

Cancer cells from a different species can be easily recognized by the immune system and rejected.

«By modifying the capsid of a virus, we could engineer a virus that is both better recognized by the immune system and that has also lost its ability to infect cells,» Manel says.

Epitopes are specific target structures recognized by the immune system of human or animal body.

In melanoma, an increase in overall mutational and neoantigen load — novel tumor - specific antigens that can be recognized by the immune system — was associated with clinical benefit from checkpoint blockade.

Recently, Swanton gave a talk at his older daughter's school on his recent work that uncovered HLA loss as a way tumors avoid being recognized by the immune system.

His lab demonstrated that neoantigens (mutated proteins unique to cancerous cells) present in most or all cells within a tumor are much more likely to be effectively recognized by the immune system.

[3] This work provided an important foundation for the idea that renal cancer is immunogenic — able to be recognized by the immune system.

Cancer cells are always present in the human body, however they are typically recognized by the immune system and destroyed before they cause any problems.

(11 - 12) The current theory is that this damaged cell material is then recognized by the immune system as foreign, leading to Hashimoto's autoimmune disease.

The novel protein source is another plus as it gives the TOTW a very safe hypoallergenic profile since many of these proteins are not yet fully recognized by the immune system of pit bulls as necessarily allergenic.

Proteins may be combined or changed into substances recognized by the immune system as foreign invaders to be attacked.

A hydrolyzed diet has the protein broken down to a level not recognized by the immune system.

Not exact matches

Autoimmunity is commonly caused by bacterial infections or overgrowth in the small intestine, in which partially digested food compounds are incorporated into bacterial cell walls and then the immune system, reacting to the bacteria, forms antibodies that also recognize food compounds, some of which might cross-react with human counterparts.

The D antigen on baby's blood can be recognized as a foreign entity by mom's immune system.

Flu vaccines work by introducing a killed version of circulating virus strains, which trains the body's immune system to recognize and attack similar invaders in the future.

Previously, Derek Danahy of the University of Iowa and colleagues showed that sepsis disrupts the immune system by reducing the amount and function of memory T cells that circulate throughout the body, recognizing and attacking specific bacteria, viruses, or cancer cells.

Vaccines work by priming the immune system to recognize the target pathogen and attack it when detected.

Pembrolizumab, which is marketed under the brand name Keytruda, works by turning off the immune system's brakes, allowing its T cells to recognize and attack cancer cells.

To survive in utero, the fetus must resist an onslaught by the mother's immune system that, most researchers agree, recognizes the father's share of the embryo as foreign and sometimes rejects it.

Antibodies are proteins made by the immune system that recognize foreign viruses and bacteria.

The immune system recognizes transplanted organs as foreign tissue by telltale proteins, called the major histocompatibility complex (MHC), that coat cell surfaces.

However, such tumor cells display unusual antigens that are either inappropriate for the cell type or its environment, and can thus be recognized by the body's immune system.

A potential solution to this problem is to reprogram other cell types into functional beta - like cells, which can produce insulin but are distinct from beta cells and therefore are not recognized or attacked by the immune system.

Two types of vaccines were used for the study: one constructed with genetically engineered DNA molecules that teach immune system cells to recognize premalignant cells expressing HPV16 E7 proteins, and one that is a non-infectious, engineered virus that targets and kills precancerous cells marked by HPV16 and HPV18 E6 and E7 proteins.

Especially critical are those genomic regions that encode viral proteins recognized by the human immune system.

The toxin produced by E. coli is too small to be recognized effectively by the human immune system, meaning that one round of infection does not provide immunity against future exposure.

Just as cells of the immune system use antibodies to recognize pathogens, researchers in this study designed antibodies to recognize a protein over-expressed by these cancer cells, namely the protein mesothelin.

Vaccines work by priming the «adaptive» immune system to recognize and attack a specific invader.

«Brain cancer cells are very good at evading the host immune system, because they do not express specific targets that can be recognized by immune cells,» said Liau, professor and vice chair of neurosurgery.

When the team monitored the vaccine's effects on the immune system in each patient, they found that both T cell types had indeed been activated by the vaccine and could recognize the neoantigens bound to HLA molecules.

Since T cells can only recognize neoantigens that are «presented» to them by HLA molecules of the immune system, a key step in making the vaccine is using computer algorithms to predict which neoantigen peptides will bind strongly to the HLA molecules for recognition by T cells.

June 2, 2016 Novel immunotherapy approach shows promise in blood cancers A protein known as STING plays a crucial role in the immune system's ability to «sense» cancer by recognizing and responding to DNA from tumor cells.

Melanoma is a tumor that is recognized by the immunological system and mechanisms leading to an anti-tumor immune response of potential value in the adjuvant setting.

Furthermore, parasite antigens that are highly immunogenic (i.e., they are recognized by the majority of individuals in an endemic area) are unlikely to be protective; rather they represent decoys specifically deployed by the parasite to distract our immune system.

The diseases can be caused by viruses as well as DNA mutations, and the data show that the drugs help the immune system to recognize and attack cancers resulting from either cause.

In the immune system, T helper cells help immune cells recognize and fight toxins by secreting a protein called interleukin 9 (IL - 9).

This new marker of senescent cells is recognized by a naturally occurring IgM antibody that belongs to the innate immune system and is likely to be involved in a natural mechanism of immune recognition and clearance of senescent cells.

These T cells already recognize the mutant p53 cancer cells, and the vaccine leads to the production of antibodies that flag the cancer for new T cells created by the immune system.

However, in a 2014 study, Dr. Sulzer's lab demonstrated that dopamine neurons (those affected by Parkinson's disease) are vulnerable because they have proteins on the cell surface that help the immune system recognize foreign substances.

Antibody a protein produced naturally by the immune system to recognize and neutralize foreign substances.

It is generally triggered by the immune system when it recognizes an invader or damage to tissue that must be kept under control.

By using different strategies to bolster the immune system, researchers can get the immune system to better recognize cancer cells and launch a stronger attack.

Furthermore, saturated fat has been shown to have numerous positive effects on health, such as improving liver health by encouraging the liver cells to get rid of their fat cells, improving the immune system's response by helping white blood cells to recognize and destroy invaders more effectively, enabling the absorption of fat - soluble vitamins by acting as their carriers, as well as improving hormonal activity by providing the building blocks for a variety of hormones that are essential to human health.

But did you know the immune system also helps to protect you from cancer by recognizing and getting rid of abnormal cells?

Since macrophages travel throughout the body and live for a long time, the β - Glucan fragments in the macrophages spread throughout the body and are recognized by other innate immune system cells.