He and his colleagues, including Janelia postdoc Fernando Amat, Janelia group leader Kristin Branson and former Janelia lab head Eugene Myers, who is now at the Max Plank Institute of Molecular Cell Biology and Genetics, have used the methodto
reconstruct cell lineage during development of the early nervous system in a fruit fly.
Not exact matches
Here, we used a marker - free approach to computationally
reconstruct the blood
lineage tree in zebrafish and order
cells along their differentiation trajectory, based on their global transcriptional differences.
We used the mutations to
reconstruct developmental
lineages of adult
cells and demonstrate that the two daughter
cells of many early embryonic
cell - doubling events contribute asymmetrically to adult blood at an approximately 2:1 ratio.