Sentences with phrase «reconstructed genomes»

By comparing DNA from modern populations with the reconstructed genomes of Neanderthals and Denisovans, they discovered that several HLA variants from the archaic groups are still around.

Sequencing the converted DNA allows scientists to reconstruct a genome - wide methylation map.

Beth Shapiro of the University of California, Santa Cruz, who led a 2017 study reconstructing the genome of the passenger pigeon, called it «super cool» because it «gives us an extinct genome on an evolutionary branch where we hadn't had any before.»

Scientists are also close to reconstructing the genomes of the dodo, the flightless bird that went extinct from Mauritius, its only home, in the late 1600s; and the great auk, which lived in the North Atlantic before dying out in the mid-19th century.

A reconstructed genome can be introduced into a mammalian egg with the cloning technique that produced Dolly the sheep.

Recent advances in ancient DNA research have opened the door for reconstructing the genomes of ancient individuals.

They reconstructed the genome of a major periodontal pathogen and produced possibly the first genetic evidence of dietary biomolecules to be recovered from ancient dental calculus.

In studying the reconstructed genome, he learned that, like modern humans, Neanderthals may have used the spoken word.

The relatively new approach allows scientists to segregate species into bins to reconstruct their genomes.

The researchers used DNA sequencing and advanced algorithms to reconstruct the genomes of a number of bacterial plankton.

We now aim to reconstruct the genomes of a number of dominant bacterioplankton species in the Baltic to learn about their ecosystem functions», says Anders Andersson.

MaxBin is an automated algorithm to reconstruct genomes from assembled metagenomic data.

By reconstructing their genomes, the scientists learned that many of these life - forms had genes that make them exceptionally good at processing carbon monoxide and hydrogen.

Their purpose was to reconstruct genomes of organisms that may contribute to biogeochemical cycling in oxygen - free subsurface environments.

Reconstructing genomes from metagenomics data provides a powerful way to understand what processes and interactions toccur in microbial communities.

The researchers were able to assign these genes to, or reconstruct the genomes in part or in whole for, 87 different bacterial species.

These methods have been used to reconstruct the genomes of previously unsequenced organisms, probe sequence variations, and explore a host of biological features across the tree of life.

Not exact matches

Thanks to powerful gene - sequencing techniques developed in the past two decades during the race to decode the human genome, researchers are beginning to reconstruct what our ancestors» microbiomes looked like, potentially going back thousands of years.

In the background, a de novo reconstructed leprousy genome.

To retrace the history of the disease, an international team of scientists, led by Johannes Krause from Tübingen University and Stewart Cole from EPFL Lausanne, have reconstructed entire genome sequences of M. leprae bacteria from five medieval skeletons that were excavated in Denmark, Sweden and the United Kingdom as well as seven biopsy samples from modern patients.

In addition to sequencing the woolly mammoth genome, Hendrik has reconstructed the diets of extinct giant sloths, debunked a hypothesis about the origin of human immunodeficiency virus (HIV) and sequenced the genome of the bacterium that caused Black Death.

Now a team of scientists has been able to reconstruct their entire genome from these meager fragments.

As researchers struggled to reconstruct ancient genomes, the world's first de-extinction had already, surreptitiously, taken place.

He and his colleagues had reconstructed the partial genome of a woolly mammoth found frozen in Siberia, and he was convinced that researchers like himself would soon be able to take bits of degraded tissue samples, extract ancient DNA and use them to piece together whole genomes of extinct animals.

Now Pääbo and his colleagues have devised a new method of genetic analysis that allowed them to reconstruct the entire Denisovan genome with nearly all of the genome sequenced approximately 30 times over akin to what we can do for modern humans.

It then connects simulated DNA fragments with overlapping sequences to reconstruct longer stretches of ancient DNA and, eventually, sections of the genome.

There's a good reason for the resemblance to armadillos, according to researchers who have reconstructed the family tree of these ancient beasts based on their mitochondrial genome, reconstructed from small fragments of DNA extracted from bits of a protective, bony carapace.

Having genomes from multiple Neandertals allows the researchers to begin to reconstruct Neandertal population history.

In the unlikely event that scientists could reconstruct a complete dinosaur genome, she doubts that any modern animal could produce an egg capable of growing a dinosaur embryo.

A new high - coverage DNA sequencing method reconstructs the full genome of Denisovans — relatives to both Neandertals and humans — from genetic fragments in a single finger bone

Scientists are sequencing a range of genomes, for example, to reconstruct the evolution of Yersinia pestis, the microbe that causes bubonic plague.

But in 2013, ultramodern DNA extraction and sequencing techniques enabled researchers to access ancient genetic codes and translate their evolutionary tales: Researchers in Denmark reconstructed a record - breaking 700,000 - year - old horse genome, and geneticists in Germany began parsing the DNA of 400,000 - year - old hominids.

The scientists obtained fragments of the viral genetic material from the insect samples and joined these fragments together like a puzzle, thus reconstructing the entire genome sequence.

The genome of Chalcolithic barley grains is the oldest plant genome to be reconstructed to date.

They reconstructed and analyzed the genomes of 15 ancient samples of maize, comparing these data to a global collection of more than 2,500 modern lines.

«Although individual mutations carry only weak signals about where a person is from, by adding information across the whole genome we can reconstruct these mixing events.

Using heavy - duty computers to sift through this mess, the team reconstructed 7280 bacterial and 623 archaeal genomes.

Now imagine a future where a successor to Venter is able to digitally reconstruct a set of the best possible sequences of human genomes and incorporate them, in pieces, into bacteria that could autonomously reproduce the sequences.

Using heavy - duty computers to sift through this mess, the team ultimately reconstructed 7280 bacterial and 623 archaeal genomes — about a third of which were new to science.

Reconstructing the detailed genome is impossible, but Galtier managed to recover two of its properties.

The team used a new approach to gene sequencing that enabled them to completely reconstruct the virus» previously unknown genome in less than 24 hours — significantly faster than conventional sequencing techniques, which can take days to weeks.

* Correction, 11 March, 11:25 a.m.: This article misstated the percentage of the best preserved individual's genome the researchers were able to reconstruct.

With mere fragments of DNA, the scientists can reconstruct entire genomes of these animals to better understand how species respond to rapid changes in the environment

From samples that contained only 0.3 % to 7 % human DNA, the researchers were able to reconstruct a rough picture of about 50 % of the best preserved individual's genome.

Then they smashed the DNA into smaller fragments, sequenced 1.05 billion base pairs, and used computer models to reconstruct partial genomes of different species.

In 2010 in a paper published inScience Translational Medicine, Lo's group showed that enough such fragments of fetal DNA are there to reconstruct the fetus's whole genome, and that it should be possible to use this DNA to test the unborn child for genetic diseases without exposing it to the risk of an invasive procedure.

It is the first time a dead person's genome has been reconstructed without DNA extracted from their remains.

The whole - genome nucleotide phylogenetic tree is reconstructed from a multiple sequence alignment of all 95 unique, fully - sequenced adenovirus genomes in GenBank and TMAdV.

Hope of reconstructing the ancestor from its inferred genes received new impetus three years ago when the first full DNA, or genome, of a bacterium was decoded.

In one of the most in - depth looks to date at a soil metagenome — all the genetic material recovered from a sample of soil — the team reconstructed portions of the genomes of 129 species of microbes.