Instead, in a Machiavellian twist, viruses
recruit human proteins to methylate DNA and thus turn off important other bits of human DNA.
When EBV infects human immune cells, a protein produced by the virus — EBNA2 —
recruits human proteins called transcription factors to bind to regions of both the EBV genome and the cell's own genome.
Not exact matches
Endocytosis of Frizzled 4 (Fz4) in
human embryonic kidney 293 cells was dependent on added Wnt5A
protein and was accomplished by the multifunctional adaptor
protein β - arrestin 2 (βarr2), which was
recruited to Fz4 by binding to phosphorylated Dvl2.
With this ability to follow viruses in real time, the Rockefeller scientists hope to tease out how HIV
recruits proteins from
human cells to do its dirty work; they also plan to look more broadly at how viruses develop.