Recently, alterations were found in the ERBB2 gene in lobular breast cancers that
recur after initial treatment.
Not exact matches
Of this high - grade type, about three - quarters will regress
after initial treatment but nearly all will
recur and need follow - up
treatment.
Gene expression profiling tests, such as Oncotype Dx, analyze the patterns of 21 different genes within cancer cells to help predict how likely it is that a women's cancer will
recur within 10 years
after initial treatment and how beneficial chemotherapy will be to her.
The following year, the FDA approved Amgen's IMLYGIC ™ (talimogene laherparepvec), a genetically modified oncolytic viral therapy indicated for the local
treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with melanoma that
recurs after initial surgery.
However, patients who don't respond to
initial treatment, or whose cancer
recurs after a remission, often have a much poorer prognosis.
In 2015, another type of immunotherapy — oncolytic virus therapy — was approved for the local
treatment of unresectable cutaneous, subcutaneous, and nodal lesions in patients with melanoma that has
recurred after initial surgery.