In youth, autophagy — controlled self - destruction, literally «self - eating» — removes and
recycles cellular waste that would otherwise compromise cellular function and regeneration of replacement structures.
Not exact matches
Scientists at the Max Planck Institute of Biochemistry in Martinsried, Germany, now discovered a new family of helper proteins that recognize labeled
cellular protein
waste and guide them efficiently to the lysosome for destruction and subsequent
recycling into their reusable compounds.
CUET proteins also associate with specific
cellular structures that target the whole complex to the
cellular waste disposal and
recycling station, the lysosome.
Autophagy, the body's mechanism for the removal and
recycling of
cellular waste, is key to rejuvenation, especially in the mitochondria, and is allowed to proceed only in the postabsorptive state, in which insulin signaling ebbs to its lowest (basal) level.
In the mitochondria, which are easily damaged due to their role as the energy production factories in cells and can themselves become a key source of
cellular damage, adequate autophagic
waste recycling is critical for rejuvenation but diminishes in aging cells.