Finally, they were also able to
reduce tumor growth in their first in vivo xenograft analysis.
Importantly, while using rosiglitazone in conjunction with targeted therapy
reduced tumor growth in both young and aged pre-clinical models, using rosiglitazone alone accelerated tumor growth in young models, while inhibiting it in aged ones.
Clinical trials lasting from one month to one year reported that consuming 25 grams of ground flaxseed daily
reduced tumor growth in women with breast cancer and decreased breast cancer risk in younger women.
Not exact matches
This recipe is full of chickpeas which help promote bone health, improve blood sugar levels
in diabetics, improve blood pressure, promote heart health,
reduce bad cholesterol, and
reduce risks of cancer and decreases
tumor growth rates.
The results, published
in Nutrition Research
in 1988, showed
reduced tumor growth rates
in animals receiving phytic acid, but not
in a control group.
They cross the blood - brain / blood -
tumor barrier, and accumulate within brain
tumor sites, where they target oncogenes, regulate cell
growth and differentiation,
reduce tumor burden and prolong survival
in our mouse models.»
The researchers took this discovery and,
in an animal model, identified a drug that is able to re-activate those immune cells and
reduce brain
tumor growth, thereby increasing the lifespan of mice two to three times.
With these
in vitro test methods, the KU researchers have shown that anti-CD44s antibody can
reduce pancreatic cancer cell
growth, metastasis and ability of the
tumors to recur after radiation therapy.
The team's recent study
in mice has found that the treatment
reduced the mass of ovarian cancer
tumors and was more effective at suppressing
tumor growth than chemotherapy.
For several years already, it is well known that
tumor growth can be
reduced by suppressing autophagy
in cancer cells.
When the researchers
reduced the amount of IL13RA2 expression
in the cancer cells, they found that the
tumor growth was significantly slower
in models.
By blocking these
in lung endothelial cells, the researchers were able to slow lung
tumor growth in mice and also
reduce the spread of metastatic
tumors.
By using molecular genetic tools to
reduce the amount of PC
in human lung cancer cells, the team observed decreased cell
growth, a compromised ability to form colonies
in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a
reduced rate of
tumor growth in mice.
By deleting the gene that expresses p300, the researchers safely
reduced Treg function and limited
tumor growth in mice.
They confirmed this by showing that
tumor growth was
reduced in mice treated with an antibody drug that targets TIM - 3 and the chemotherapy agent paclitaxel, as compared to treatment with paclitaxel alone.
To test this, researchers inhibited the ability of Runx2 to be phosphorylated
in cancer cells and found that
tumor growth was
reduced.
In particular, the combination
reduced tumor growth and angiogenesis, the process by which
tumors recruit blood vessels to feed their expansion.
«We also found that methylnaltrexone
reduced tumor growth and spread
in several cancer models,» Singleton said.
They also tested Rapalink's ability to inhibit
tumor growth in animal experiments, and found that it
reduced the size of
tumors that were resistant to first - or second - generation mTOR inhibitors.
The researchers then turned to a JAK2 - specific inhibitor now known as BSK805 which markedly
reduced TNBC
tumor growth in mice when paired with chemotherapy.
In the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in Oncotarge
In the treated mice, the treatment strongly
reduced the
tumor growth with no toxicity to the mice, reports the study
in Oncotarge
in Oncotarget.
These compounds have been shown to inhibit cancer cell
growth, induce cancer cell apoptosis, and
reduce tumor volume
in mice (14, 15, 16, 17).
The importance of stromal POSTN was also demonstrated
in another study
in which orthotopic inoculation of gastric cancer cells into Rag2 − / −; Postn − / − mice
reduced tumor size, decreased invasiveness, and decreased
growth compared to Rag2 − / −; Postn + / + mice (Kikuchi et al., 2014).
URBANA, Ill. — Years of research
in University of Illinois scientist John Erdman's laboratory have demonstrated that lycopene, the bioactive red pigment found
in tomatoes,
reduces growth of prostate
tumors in a variety of animal models.
Knowing that insulin can stimulate the
growth of blood vessels, «our expectation was that knocking out insulin signaling
in these cells might slow the
growth of blood vessels and
reduce tumor formation
in these mice,» Rask - Madsen says.
The conjugate, which they named «chemocoxib A,»
reduced growth of COX - 2 positive
tumors in mice by 50 percent, but didn't have any effect on
tumors that didn't express the enzyme.
In some of the children, the drugs blocked tumor growth; in others, they reduced tumor siz
In some of the children, the drugs blocked
tumor growth;
in others, they reduced tumor siz
in others, they
reduced tumor size.
: Therapy with MIA - 602 significantly
reduced tumor growth and enhanced the efficacy of doxorubicin
in both cell lines.
Combination therapy resulted
in significantly
reduced growth compared to controls (P < 0.001), and
tumors treated with MIA - 602 (P < 0.05) or doxorubicin (P < 0.001)(figure 1b).
Conversely, blocking CXCR4 / CXCL12 pathway
in triple - negative (TN) BC does not
reduce tumor growth, and can even increase metastatic spread.
Results: Therapy with MIA - 602 significantly
reduced tumor growth and enhanced the efficacy of doxorubicin
in both cell lines.
Furthermore,
in COX - 2 deficient mice a decrease
in VEGF, and both
reduced angiogenesis and
tumor growth were observed [40].
Furthermore, we found that human IL - 15 mediated insulin - like
growth factor - 1 production
in CD215 + myeloid cells and blocking IGF - 1
reduced the
tumor - promoting effect of IL - 15.
But no enhanced or
reduced tumor growth was observed
in mice when human IL - 15 was used.
Recent studies have shown that curcumin can
reduce growth of new blood vessels
in tumors and metastasis and basically help kill off cancerous cells.
Lycopene, which is found
in tomatoes, has actually been shown
in some studies to
reduce tumor growth, and can help protect against lung, stomach, colon, oral, breast AND cervical cancers!
Possible reduction
in certain types of cancer: «It appears to work primarily by blocking the
growth and metastatic spread of
tumors, controlling the cell cycle, and by
reducing inflammation.»
● Protect cells, slow
tumor growth and
reduce side effects of chemotherapy treatment
in cancer patients.
In laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animal
In laboratory studies, the turmeric (curcumin) herb
reduced the
growth of cancerous cells and inhibited the
growth of
tumors in the laboratory test animal
in the laboratory test animals.
In some cases, a person with a tumor in the pituitary gland could have reduced human growth hormone production, but the reverse could also be tru
In some cases, a person with a
tumor in the pituitary gland could have reduced human growth hormone production, but the reverse could also be tru
in the pituitary gland could have
reduced human
growth hormone production, but the reverse could also be true.
Dr. Mechoulam: There are several groups that have found it effective
in reducing tumor growth.
This mineral has been known to
reduce inflammation, decrease
tumor growth, and has the ability to stimulate the production of killer T - cells — which improves immune function
in response to infections.
: The aforementioned catechins, known as a potent antioxidants, contained
in the matcha leaf may play a major role
in preventing and
reducing the risk of cancer as they activate detoxification enzymes
in the body and help improve immune system function, which can repair damaged cells and prohibit
growth of
tumors.
Researchers report that curcumin
reduces all pro-inflammatory molecules
in cartilage cells and
in membranes that line the joints, among them
tumor necrosis factor — which destroys joint cartilage — and vascular endothelial
growth factor, which promotes excessive
growth of blood vessels
in inflamed joints.
Contained
in the juice of a pineapple are two digestive enzymes which help thin the blood
in a fashion similar to the drugs aspirin and Coumadin, helps
reduce pain and inflammation, and may help slow
tumor cell
growth.
Multiple studies
in laboratory's show that curcumin can
reduce the
growth of
tumors, the spreading of cancer, and contribute to overall cancer cell death.
They evaluated graviola extract and found that it contains compounds that play a role
in regulating the metabolism, survival and
growth of cancer cells, shrinking
tumors and
reducing cancerous cells» ability to grow and spread.
Cancer:
In 1914, Nobel Laureate Payton Rous, Father of the
tumor virus, suggested restricted food intake
reduced tumor growth by
reducing tumor blood supply [45].
:
In 1914, Nobel Laureate Payton Rous, Father of the
tumor virus, suggested restricted food intake
reduced tumor growth by
reducing tumor blood supply
A couple of studies have shown that eating flaxseeds may
reduce markers of
tumor growth in women with breast cancer, and may also
reduce cancer risk (10, 11, 12).