Sentences with phrase «reduced cell population»

The diminished ability for cells to grow is strongly associated with the aging process, with the reduced cell population directly contributing to weakness, illness, and organ failure.

Not exact matches

Subsequent tests revealed that the treatment had reduced the visible cell population by a factor of 100 thousand, compared with an untreated cell culture, within the space of just 20 days.

They demonstrated that non-obese diabetic (NOD) mice treated with a specific (AID / RAD51) pathway inhibitor had larger populations of certain B cells that were capable of suppressing diabetogenic T cell responses, and greatly reduced T1D development, compared with untreated controls.

The percentage of malignant T cells was reduced significantly in nine of ten tested participants, three of whom had complete eradication of the malignant population, and one of whom had a 99.6 percent reduction.

This population of cells was also reduced in the bone marrow of T1D patients.

With the absence of TRF2, stem cell like characters in terms of CD44, CD24 and Oct4 were also downregulated which correlated well with reduced spheroidal population.

Upon transfer of aged donor CD4 T cells to young hosts, there was significantly reduced expansion and germinal center (GC) differentiation of the antigen - specific B cell population after immunization.

While the plating efficiency of the V+S + fraction was reduced and produced 4-fold less colonies than the V − S + fraction, both fractions gave rise to identical colonies that contain equivalent populations of V + and V − cells (Figure 7A, Table 1).

In addition to identifying a cell population with enhanced reprogramming efficiency, we also identified an SSEA3 - negative population with either significantly reduced reprogramming efficiency or no reprogramming ability.

In Thy1 - PE labeling experiments, Ccr6 KO mice showed reduced frequencies of labeled cells, a result that was most significant for the Vγ4 + population (Figure 4G).

Once the fat cell population of an area has been reduced, it can't re-populate.

This means that half of the cancer cell lines did not thrive in 20 mmol / L of ascorbic acid, while another half were more resistant and required a higher dose to effectively reduce the population by 50 % (EC50)[16].

«What we have to recognize... is that if cancer is a mitochondrial metabolic disease and you get cancer because of mitochondrial failure in certain populations of cells and certain tissues, if you prevent your mitochondria from entering into this dysfunctional state... [then] the probability of getting cancer is going to be significantly reduced.

The Fab fragment of mAb 5.91, pre-incubated with canine IgE, reduced the binding of canine IgE to the monocyte cell population from 15 % to 5.6 %.

This demonstrated that the Fab fragment of mAb 5.91 was even more effective in reducing the binding of IgE to the monocyte cell population than the intact mAb 5.91.

Results showed that the whole mAb 5.91 molecule reduced the amount of binding of canine IgE to the monocyte cell population from 15 % to 7.7 %.