Sentences with phrase «reduced cell viability»

ONC201 synergistically reduced cell viability in combination with cytarabine and 5 - azacytidine in AML cells.

Thus, lethal toxin - mediated down - regulation of IL - 22 was not due to reduced cell viability and instead suggested interference with a signaling pathway that regulates IL - 22 production.

In the laboratory, knocking out PRMT5, or another core component of the splicing machinery in human lymphoma cells lines, also reduced cell viability.

Not exact matches

In testing on two mouse cell lines, the drug combination reduced the viability of cancer cells by about 50 percent when compared with everolimus alone, according to the findings.

In BRCA - deficient cells, treatment with the molecule resulted in reduced cell growth and viability.

«The modification of bacterial cells with polypyrrole is anticipated to improve the electrical conductivity of bacterial cells without reducing their viability,» the authors explained.

Oxidized phospholipids derived from ozone - treated lung surfactant extract reduce macrophage and epithelial cell viability.

Sesamol has been shown to inhibit melanin synthesis in mouse melanoma cells, resulting in reduced viability and proliferation of the cells.