Sentences with phrase «reduced effects of treatments»
The authors noted that low croploads during the study period may also have contributed to reduced effects of treatments on cherry quality characteristics other than size.
https://www.sciencedaily.com/ Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The study focused on a progesterone gel treatment that was found to be effective in reducing early births of singletons but did not have the same effect with multiples.
Before beginning treatment, talk to your child's pediatrician about your concerns regarding potential side effects and how to reduce your child's risk of complications.
«The goals of asthma treatment are to reduce the patient's symptoms, help ensure that they can maintain their normal activities, perform well on pulmonary function tests and minimize asthma associated risks such as future asthma attacks and medication side effects,» said Jennifer McCracken, UTMB assistant professor in the department of internal medicine, division of allergy and immunology.
«But, we wanted to examine if there were any treatments or interventions that could aid to minimize the effect of sleep loss by reducing the severity of pain experienced after surgery.»
«Our study suggests that in patients with heart failure and atrial fibrillation, catheter ablation is an effective alternative treatment that can help patients avoid or discontinue this drug to reduce the risk of these long - term side effects.»
«The treatment method involves administering these substances over the course of a day to reduce the rewarding effect.
By targeting different hormones that help the body manage its own insulin levels — and by reducing side effects such as weight gain — three drugs recently approved by the FDA avoid most of the major problems associated with past diabetes treatments.
Pending further research, the evidence may point to possible treatments to reduce the effects of low blood oxygen on mood and suicidal thoughts.
The recommendations aim to reduce unnecessary treatment for prostate cancer and potential long - term side effects from it, according to the University of North Carolina Lineberger Comprehensive Cancer Center member who first - authored the report.
«Shortening treatment regimens and reducing the required doses may be a promising strategy to reduce the incidence of bedaquiline - related adverse effects and thereby improve multidrug - resistant TB treatment outcomes,» says Gupta.
While lithium carbonate has been very effective for the treatment of mania in bipolar disorder, and credited for reducing suicides in depressive phases of the disease, patients who take lithium carbonate are often noncompliant because of adverse effects, including hand tremor, diarrhea, vomiting, weight gain and decreased thyroid function.
However, all other outcomes failed to show an effect of baclofen: baclofen did not increase abstinent days or decrease number of heavy drinking days during treatment, neither did it reduce rates of alcohol craving, anxiety or depression.
The combination of the two drugs could potentially shorten treatment time, reduce the side effects of bedaquiline and improve patient outcomes for those suffering from TB.
«The advantage of being able to deliver methotrexate in this targeted way is to be able to gain the benefits from this key treatment of RA, while reducing the risk of adverse effects that are more frequent at high doses,» concluded Dr Macor.
«New soft material could reduce complications for women suffering from urinary incontinence: Researchers have developed a novel implantable material which could reduce the number of debilitating side - effects that occur as a result of using a material that is too rigid for surgical treatment of incontinence.»
Researchers at the University of Sheffield have developed a novel implantable material which could reduce the number of debilitating side - effects that occur as a result of using a material that is too rigid for surgical treatment of incontinence.
«This is why we're diligently working to employ several strategies that we hope will lead us to reaching our ultimate goal of developing the best therapy possible — a therapy that can be given to patients as a first line of defense, greatly reducing the side effects of cancer treatment and leading to a cure.»
According to Dr. Rosamilia, early treatment not only can reduce the pain and severity of the disease, but also can help prevent potential side effects like eye problems, infection, and a condition called post-herpetic neuralgia, which causes pain, numbness, itching and tingling.
«It's important to understand the mechanisms of action of chemotherapy on spermatogenesis to help clinicians make informed decisions on adjusting treatment, reducing side effects, and better advising patients on family planning,» says INRS's Dr. Géraldine Delbès, reproductive toxicology specialist and the author in charge of this study.
A team of researchers at the University of Georgia has developed a non-invasive method of delivering drugs directly to cancerous tissue using magnetic forces, a form of treatment that could significantly reduce the toxic side effects of chemotherapy.
Statistical modeling of the results revealed that, on average, patients experienced significantly reduced scores for the active treatment, though the size of the effect in individual patients varied.
«Our collaboration with scientists at Charles Gerhardt Institute was important to the success of this two - photon activated technique,» said Tamanoi, «which provides controls over drug delivery to allow local treatment that dramatically reduces side effects.»
Not only does this reduce the effect of a chemotherapy treatment, but it also creates hydrogen fluoride, a gas that can be harmful both to the patients and to the medical equipment.
Researchers trying out new treatments need to make sure any effect the treatment has in reducing the incidence of heart disease is statistically significant.
The authors point to studies of harmful and beneficial effects of thrombolytic and antiarrhythmic drugs for myocardial infarction, for example: «Not only would systematic reviews... have reduced waste resulting from unjustified research, they would also have shown how to reduce morbidity and sometimes mortality, both in patients allocated to relatively less effective or actually harmful treatments in unnecessary trials, and in patients generally,» the authors write.
Merkx: «By directly linking the measurement of antibodies to the treatment of the disease, we may be able to prevent side - effects and reduce costs in the future.»
Newer evidence suggests that the shorter course of treatment does not reduce the benefits of therapy; in addition this can reduce antibiotic - related side effects, the risk of Clostridium difficile, a serious diarrheal infection, antibiotic resistance and costs, said Dr. Kalil.
The research, which appears in the journal The Lancet Oncology, should aid efforts to reduce and better manage the late effects of cancer treatment.
«Cancer doesn't sleep: MYC oncogene disrupts clock, metabolism in cancer cells: Findings inform time - dependent treatment for reducing side effects, increasing effectiveness of cancer medications.»
Possible long - term interventions to reduce mortality and morbidity after high exposures end include disease screening, reducing important co-exposures, treatment and health services resource planning, and increasing public awareness of arsenic health effects.
Although fewer activated T cells were generated after a treatment with 3pRNA, the positive effect of the leukemia therapy was not reduced to a measurable degree.
«While there are clearly other factors that can cause these types of abnormalities, including genetic vulnerabilities, demonstrating that immune activation alone can produce these effects offers new hope for treatments that might reduce their severity, or prevent them altogether, in certain individuals.»
«This research is important because it identifies a way to reduce some of what, in medical treatment, are usually thought of as THC's unwanted side effects, while maintaining several important benefits including pain reduction.»
But treatment to reduce 5HT2AR did not change other effects of THC, including pain relief.
The drug — named mepolizumab — can replace traditional, steroid - based treatments for a specific subset of patients, resulting in improved outcomes and reduced side effects.
Noelle Frey, MD, an assistant professor of Hematology - Oncology, will present results in 27 adult patients with acute lymphoblastic leukemia (ALL), identifying an optimal dose and infusion regimen that should improve treatment response while reducing potential for side effects.
A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a study from researchers at the University of Michigan Comprehensive Cancer Center.
The adverse effects of epinephrine appeared to be unaffected by the use of post-resuscitation medical treatments, such as techniques to cool the body to reduce tissue damage or interventions to restore the flow of blood through blocked arteries.
Although doctors have long incorporated personal information like family history into treatment plans, personalized medicine holds the promise of revolutionizing medical care by using knowledge of molecular biology and genetics that will allow more precise diagnoses, better diagnostic tests, greater predictability of disease course, more successful therapies by targeting the right treatments to the right patients, and improved patient safety by selecting drugs and their proper dosage to reduce adverse side effects.
«This paves the way for a whole new class of anti-inflammatory agents, inspired by quebecol, that could compensate for the low efficacy of certain treatments while reducing the risk of side effects.»
A move to lengthen limbs internally rather than via an external scaffold could reduce the effects of painful treatments, especially among younger patients
He says that the new nanoparticles accumulate preferentially in tumors, which could drastically reduce the side effects of current cancer treatments that usually kill healthy cells along with the targeted cancer cells.
Other projects include an analysis of regional variations of cancer treatment in Texas, a study of the effect of smoking bans on hospitalization rates, and a study of whether shared savings programs for physicians can reduce overall patient health care expenditures.
«This research shows great promise to reduce adverse effects for people undergoing breast cancer treatment,» said Timothy M. Block, PhD, president of the Baruch S. Blumberg Institute, which manages PCARMRC.
July 13, 2016 Simple procedure could improve treatment for common eye disease: Rejuvenating the cornea could reduce the need for cornea transplants A new, minimally invasive procedure appears to be effective for many patients with Fuchs endothelial dystrophy (FED), a common eye disease, without the potential side effects and cost of the current standard of care, a cornea transplant.
Restricting the movement of the drug also reduces potentially harmful secondary effects on other parts of the body — for instance, the hair loss that can result from toxic cancer treatments, or the loss of so - called good bacteria due to antibiotic use.
J147 treatment also resulted in a significant effect on Aβ metabolism, reducing levels of soluble Aβ without an effect on plaque density or size (Figure 2).
By engineering the devices to release their payloads only once they reach the site of the tumor, the researchers hope to reduce dosages and also limit the side effects of conventional treatments.