Importantly, at both time points examined, there were no differences in locomotor activity and / or pain sensitivity between rat groups (Additional file6: Figure S5), suggesting that
the reduced fear conditioning responses (freezing behavior) in transgenic rats were not influenced by any differences in sensitivity to pain or by increased locomotion.
Not exact matches
Aged C3 - deficient mice also performed significantly better than WT mice in the contextual
fear conditioning task, which evaluates memory associated with aversive stimuli, and C3 - deficient mice display
reduced anxiolytic behavior, evaluated via the elevated plus maze and open - field assessment.
Classical
Conditioning is the Scientific Term for the type of training that is used to
reduce or cure an animal's
fear.
This finding is interesting, in that attachment figures are likely to increase μ - opioid levels and thus may serve as prepared safety stimuli —
reducing conditioned fear responses and enhancing learned safety — through μ - opioid — related processes.
The implication of these findings is that μ - opioids are involved in
reducing conditioned fear responses and enhancing
fear extinction or learned safety.
Furthermore, people with high levels of CU traits (psychopathic personality) have been shown to have three specific cognitive and emotional deficits; a poor
conditioned fear response,
reduced ability to recognise
fear, and deficits in stimulus - reinforcement tasks (see Moul et al. [12] for a review).