Silymarin (milk thistle) significantly
reduced infarct size at 500 mg per kg dose, as shown by the altered serum and heart tissue.
Researchers are planning to extend the clinical trial to a much larger number of patients in a multinational study, to demonstrate not only
a reduced infarct size, but also a reduced mortality in patients who receive early metoprolol during transit to hospital.
In an editorial accompanying the published article in Circulation, experts from the Technische Universität and the Munich Heart Alliance, Gjin Ndrepepa and Adnan Kastrati, affirmed that, if confirmed by a subsequent analysis of large numbers of patients, the results of METOCARD - CNIC trial are likely to lead to a change in clinical practice: «In this regard, a pharmaco - protective strategy able to
reduce infarct size by 20 percent when used in conjunction with primary PCI nurtures great hope in clinical benefit.»
DITPA, a Thyroid Hormone Analog,
Reduces Infarct Size and Attenuates the Inflammatory Response Following Myocardial Ischemia.
Cell therapy has been shown to be effective in
reducing the infarct (scarring) caused by a heart attack as well as improving heart function when certain cell types are used — particularly cells from a person's own fat (adipose tissue).
It has been demonstrated that MSCs injected into the infarcted myocardium significantly improve the left ventricular function and
reduce the infarcted area size.
Progesterone significantly
reduces infarct area, lipid peroxidation levels and activity of myeloperoxidase in myocardial ischemia / reperfusion injury.
Not exact matches
In addition to producing effects on cortical excitability, stroke may affect the balance of trans - callosal inhibitory pathways between motor primary areas in both hemispheres: the affected hemisphere (AH) may be disrupted not only by the
infarct itself but also by the resulting asymmetric inhibition from the unaffected hemisphere, further
reducing the excitability of the AH.