Other sources of dry eye include drug toxicity (antibiotics such as sulphadiazine and sulphasalazine can cause temporary or permanent dry eye in some animals), drug - induced reaction (atropine and topical anesthetics temporarily
reduce tear production), neurological impairment (damage to the nerves leading to the
lacrimal glands), removal of the third eyelid (see Cherry Eye), systemic disease (e.g. distemper), chronic conjunctivitis, trauma to the tear glands, hypothyroidism, congenital disease (some dogs are born without
lacrimal glands), breed predisposition.