Sentences with phrase «reduced metastasis»

Additionally, the study showed that genetic knockdown of RASAL2 gene can lead to reduced metastasis in breast cancer mouse model.

Anti-inflammatory treatment reduced metastasis in the mice, and existing clinical data also suggest that perioperative anti-inflammatories reduced early metastatic recurrence in breast cancer patients.

This is especially so since in animal models of ovarian cancer, Fan and the team demonstrated that FER's suppression reduced cancer cell motility and sharply reduced metastasis.

Statement from Breast Cancer Care on research from the Queen's Medical Centre, Nottingham, presented to the seventh European Breast Cancer Conference on the use of beta - blockers to help reduce metastasis and improve survival in breast cancer patients.

So a drug that blocks DDR2 from binding with collagen won't destroy the tumor, but it could inhibit the invasion of these tumors into surrounding tissue and reduce metastasis.

This has led to the demonstration that blocking the mobilisation of neutrophils can reduce metastasis in our preclinical models.

Not exact matches

«When we reduced this enzyme expression in prostate cancer cells, we found a lower prostate cancer bone metastasis,» he said.

«Our work predicts that reducing the number of circulating cancer cells produces less metastasis,» Pellecchia said.

«The possibility of preventing or slowing down the spread of cancer cells via the lymphatic system is an attractive one, as it could reduce the risk of metastasis to other organs.»

With these in vitro test methods, the KU researchers have shown that anti-CD44s antibody can reduce pancreatic cancer cell growth, metastasis and ability of the tumors to recur after radiation therapy.

Now, University of Missouri researchers have found that luteolin, a natural compound found in herbs such as thyme and parsley, and vegetables such as celery and broccoli, could reduce the risk of developing metastasis originating from triple - negative breast cancer in women.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

In future work, the Eischen laboratory aims to further understand the role of lncRNAs in ovarian cancer, and potentially translate their findings into clinical applications to reduce ovarian cancer metastasis.

It has been known for decades that warfarin, the most widely used anticoagulant worldwide, reduces tumor metastasis in model systems.

The combination of these two aspects of the immune response reduce risk of recurrence and discourage spreading or metastasis of the cancer.

As in the knock - out mice, aggressive tumors failed to thrive and were reduced to low - grade tumors looking more like cysts; metastasis, while not completely abolished as in the knock - out mice, was reduced some 70 percent.

To gain an understanding of the mechanism that connects low mtDNA levels with a cellular change that leads to cancer and metastasis, Guha, Avadhani and their colleagues set up two systems by which they could purposefully reduce the amount of mtDNA in a cell.

By restoring protein encoded by PARD3 levels, both, cell lines and animal models of mice, we observed that regulating de novo polarization of cells, significantly reduced the risk of metastasis.

Oral administration of mebendazole in mice elicited a strong antitumor effect in a subcutaneous model and reduced lesions in experimentally induced lung metastasis without any toxicity when compared with paclitaxel - treated mice [9,20].

Taking apalutamide also reduced other signs of disease progression — including development of imaging - confirmed metastasis or symptoms such as bone pain — and death from any cause.

A peptide that inhibits function of Myristoylated Alanine - Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis

Forced expression of fascin1 in colorectal cancer cells increased their migration and invasion in cell cultures and caused cell dissemination and metastasis in vivo, whereas suppression of fascin1 expression by small interfering RNA reduces cell invasion.

Drugs that blocked the opioid receptor reduced cancer growth and helped prevent invasion and metastasis.

Recent studies have shown that curcumin can reduce growth of new blood vessels in tumors and metastasis and basically help kill off cancerous cells.

«consumption of abundant alkaline - forming foods can result in improvement in bone mineral density (BMD) and muscle mass, protection from chronic illnesses, reduced tumor - cell invasion and metastasis, and effective excretion of toxins from the body.

Green tea reduces C - reactive protein and green tea catechins can successfully banish cancer cells, by slowing metastasis, inhibiting cell proliferation and inducing apoptosis.

Keto diet is a cancer suppressor and reduces its growth and metastasis.

In advanced mammary cancers where metastasis has occurred or in which the tumor is fixed to the underlying tissues, surgery will not be curative but may be considered an option to reduce local tumor - burden and improve quality of life.