Sentences with phrase «reduced proliferation»

These include a reduction in B cell differentiation to plasma cells and a reduced proliferation of T cells.

They found that higher end concentrations of the drug led to reduced proliferation, which would likely negatively affect the muscle's ability to heal and repair itself.

Studies (like this one) have even demonstrated a reduced proliferation of cancer cells in subjects who practiced intermittent fasting, and another study showed that alternate day fasting led to better reception of chemotherapy in cancer patients and a higher cure rate.

The Zika virus is known to negatively impact the growth of fetal brains and a group of researchers publishing in the journal Cell Stem Cell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferation.

These opposite clinical outcomes - arising from reduced proliferation and overproliferation respectively - can be explained in light of the tissue - and developmental - specific requirements for centrosome functions.

In search of a mechanism behind the finding that HIV / gp120 reduced proliferation of aNPCs, the scientists studied the effect of the protein on the cell cycle.

Furthermore, when the team suppressed STAP - 2, the prostate cancer cells showed reduced proliferation and did not form a tumor when transplanted into mice.

Overexpression of GARP reduced the proliferation and activation of B cells.

In their models, abatacept reduced the proliferation and activation of effector T cells.

Treatment of vestibular schwannoma cells with mifepristone reduced their proliferation rate by 80 percent.

Through these effects, the PERY peptide reduced the proliferation of several (but not all) cancer cell lines in culture and inhibited the growth of a human breast cancer xenograft in mice.

Decreased IGF type 1 receptor signaling in mammary epithelium during pregnancy leads to reduced proliferation, alveolar differentiation, and expression of insulin receptor substrate (IRS)-1 and IRS - 2.

ORIGINAL ARTICLE — Layfette Journal & Courier 3:42 p.m. EDT April 23, 2015 Chris Morisse Vizza and Chris Morisse Vizza, [email protected] Copper Moon Coffee wants to reduce the proliferation of plastic single - serve brewing pods dumped in landfills, president Cary Gutwein said.

In the paper, the researchers show for the first time that ANG simultaneously reduces proliferation of stem cells and promotes proliferation of myeloid progenitor cells that give rise to mature myeloid cells.

An experimental drug that targets abnormally high levels of a protein linked to cancer growth appears to significantly reduce the proliferation of prostate cancer cells in laboratory cell cultures and animals, while also making these cells considerably more vulnerable to radiation, according to results of a study led by Johns Hopkins scientists.

Abrogation of PIK3CA or PIK3R1 reduces proliferation, migration, and invasion in glioblastoma multiforme cells.

We can continue down the same path for used nuclear fuel that we have been on for the last 50 years, or we can develop an approach that brings the benefits of nuclear energy to the world while also reducing proliferation concerns and nuclear waste.

Inhibition of Notch signaling reduces proliferation of stem cells, induces cell death, and down - regulates non-canonical Wnt5a, suggesting that the Notch pathway contributes to maintenance and motility of the stem cells.

Fuel is encapsulated in the core, which the company says significantly reduces proliferation risk and enhances overall safety for the user.

Acai containing polyphenolics could reduce proliferation of HL - 60 leukemia cells in vitro.

Both antioxidant compounds work reducing the proliferation of reactive oxygen species in cells, preventing mutations and dead due to oxidative stress.

This disease - fighting nutrient can slow the growth and development of new blood vessels that nourish tumors, increase a type of programmed cancer cell death known as apoptosis and reduce the proliferation of new cancer cells.

Naturally found in sternal chicken Collagen Type II, chondroitin sulfate has anti-inflammatory activity that reduces joint swelling, maintains synovial fluid levels, and spacing between the joints.10 Furthermore, chondroitin sulfate reduces the proliferation of proteins to reduce joint inflammation.11

And modern nuclear technology can reduce proliferation risks and solve the waste disposal problem by burning current waste and using fuel more efficiently.

Internationalization of both ends of the fuel cycle can reduce proliferation risk.

It must produce significantly less costly, cost - competitive clean electricity, be safer, produce significantly less waste and reduce proliferation risk.

Not exact matches

Try as they might, the proponents of a sorry belief system that for so long held the world back are going to find that the proliferation of information and knowledge in this age will see their bigoted views reduced to the margins of history.

High dosages of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another study using rats and humans demonstrated lack of reproductive toxicity.

Acute Psychosocial Stress Reduces Cell Survival in Adult Hippocampal Neurogenesis without Altering Proliferation.

Because while we are reducing taxes my friends we also have to tackle a major structural problem which is the proliferation and expense of local governments.

The government policy is also due, in part, to the emergence of new nuclear energy technologies that, if successfully developed and implemented, could increase nuclear plant safety while also reducing costs and the risk of nuclear proliferation.

Keating notes that «the implication, which isn't proven, but is quite exciting, is that by enhancing human cardiomyocyte proliferation after heart injury, one may be able to enhance cardiac regeneration and reduce cardiac scarring.»

Fast - neutron reactors could extract much more energy from recycled nuclear fuel, minimize the risks of weapons proliferation and markedly reduce the time nuclear waste must be isolated

Mammalian hairs and avian feathers develop from a similar primordial structure called a «placode»: a local thickening of the epidermis with columnar cells that reduce their rate of proliferation and express very specific genes.

Overall, the presence of B lymphocytes was associated with increased tissue proliferation, reduced cell death and a more supportive environment for wound healing.

Furthermore, when they blocked the action of the gene using RNA interference, the cell proliferation index was reduced.

Although the rationale has morphed over time, the end result is similar: a proliferation of fat - reduced — and often correspondingly starch - rich and sugar - rich — foods and diets, with paradoxical warnings and caveats about eating healthy, high - fat foods, such as those rich in nuts and vegetable oils.»

«We recognize that the gravest terror threat we face — a nuclear attack made possible by nuclear proliferation — requires a comprehensive strategy for reducing the world's nuclear stockpiles and preventing the spread of those armaments,» it says.

Changes in chromatin may help reduce unwanted stem cell proliferation and can be achieved by adding drugs to experimental cultures in Petri dishes, Kwan said.

The pathway then uses the tumor's metabolism to break down glucose and use its energy to reduce cell death and maintain proliferation.

Specifically, it reduces the production of inflammatory compounds like prostaglandins, slows white blood cell proliferation and even kick - starts apoptosis in existing white blood cells, causing them to break down.

The proteasome is a novel downstream target for the anti ‐ cancer drug palbociclib inhibiting proliferation by reduced proteasomal association with its inhibitor EMC29.

Satellite cell proliferation is reduced in muscles of obese Zucker rats, but restored with loading.

Insulin is a key ingredient for the growth and proliferation of normal stem cells, and the study demonstrated that insulin resistance also reduces the ability of the iPSCs to grow and proliferate.

This supported work from Bartholomew et al 120 showing that the addition of IL - 2 to MLR / MSC co-cultures reduced MSC suppression and restored T cell proliferation.

MSCs impair the differentiation of monocytes or CD34 + HSCs into DCs by inhibiting the response of the former to maturation signals, reducing the expression of co-stimulatory molecules and hampering the ability of the former to stimulate naive T cell proliferation and IL - 12 secretion 33, 34, 35.

Various studies demonstrated that stem cells treatment reduced scar burden, affected fibroblast proliferation, reduced Type I and Type III Collagen synthesis, improved ventricular function and affected left ventricular geometry.

In human gastric tissue, however, gastric epithelial cell proliferation is significantly higher but apoptotic indices are lower among persons colonized with cag + compared to cag - strains or uninfected persons leading us to postulate that reduced rates of cell loss, when accompanied by hyperproliferation, may heighten retention of mutagenized cells, which could predispose towards cancer.

Their limited proliferation capacity makes it necessary to prepare MEF cells often, creating batch - to - batch variability and reducing reproducibility in derivation of iPS cells.

We observe that a stress of 10 kPa is sufficient to drastically reduce growth by inhibition of cell proliferation mainly in the core of the spheroid.