Sentences with phrase «reduced side effect profile»
The agent, approved in 1995, has the benefit of a reduced side effect profile compared to its traditional counterpart — delivery of free doxorubicin.
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They note that a related compound with better pharmacological profiles than CLP257 was as effective in reducing pain in rats as an existing pain treatment called pregabalin, but it lacked the undesirable motor side effects that are often seen with that drug.
Importantly, IMGN632 was effective at concentrations well below those that affected normal bone marrow cells, suggesting the potential for efficacy in AML patients with reduced likelihood of myelosuppressive side effects and favorable safety profile.
Anticonvulsants have also been used to reduce aggression.31 The side effect profile and monitoring requirements provide similar limitations to the anticonvulsants.