Sentences with phrase «reduced tumor growth»

Animal studies that inactivate the IGF1 receptor show reduced tumor growth.

: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply

Cancer: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply [45].

Clinical trials lasting from one month to one year reported that consuming 25 grams of ground flaxseed daily reduced tumor growth in women with breast cancer and decreased breast cancer risk in younger women.

Interestingly enough, none of the diets (despite reduced tumor growth) increased the life expectancy of the rodents.

After 30 days, there was a reduced tumor growth markers from 30 percent to 71 percent.

But no enhanced or reduced tumor growth was observed in mice when human IL - 15 was used.

Inhibition of FABP4 also reduced tumor growth and the ability of tumors to generate new blood vessels.

Results: Therapy with MIA - 602 significantly reduced tumor growth and enhanced the efficacy of doxorubicin in both cell lines.

: Therapy with MIA - 602 significantly reduced tumor growth and enhanced the efficacy of doxorubicin in both cell lines.

On the other hand, reducing copper levels reduced tumor growth.

In the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in Oncotarget.

«We also found that methylnaltrexone reduced tumor growth and spread in several cancer models,» Singleton said.

In particular, the combination reduced tumor growth and angiogenesis, the process by which tumors recruit blood vessels to feed their expansion.

Moreover, injection of 5E5 CAR T cells into mice with leukemia or pancreatic cancer reduced tumor growth and increased survival.

Importantly, while using rosiglitazone in conjunction with targeted therapy reduced tumor growth in both young and aged pre-clinical models, using rosiglitazone alone accelerated tumor growth in young models, while inhibiting it in aged ones.

The results, published in Nutrition Research in 1988, showed reduced tumor growth rates in animals receiving phytic acid, but not in a control group.

Avastin, from Genentech, and Erbitux, from ImClone Systems, are the first drugs to reduce tumor growth from colon cancer that has spread to other parts of the body.

Finally, they were also able to reduce tumor growth in their first in vivo xenograft analysis.

Recent research suggests that a novel material called nanosponge could be up to five times more effective at reducing tumor growth than direct injection.

: We conclude that treatment of triple negative breast cancers with growth hormone - releasing hormone antagonists reduces tumor growth and potentiates the effects of cytotoxic therapy by nullifying drug resistance.

Conversely, blocking CXCR4 / CXCL12 pathway in triple - negative (TN) BC does not reduce tumor growth, and can even increase metastatic spread.

Lycopene, which is found in tomatoes, has actually been shown in some studies to reduce tumor growth, and can help protect against lung, stomach, colon, oral, breast AND cervical cancers!

Reducing IGF - 1 levels has a direct on decreasing insulin which may reduce tumor growth and cancer over time by following a ketogenic diet.

Dr. Mechoulam: There are several groups that have found it effective in reducing tumor growth.

The healthy fruit, pomegranate also contains flavonoids that have shown great promise during test tube experiments for reducing tumor growth.

Prechemotherapy short - term fasting has been shown to help reduce tumor growth by supporting chemotherapies» efficacy; evidence also suggests it can lessen chemotherapies» damaging side effects.

[12] Suma has been shown to accelerate wound healing, reduce tumor growth, and regulate blood sugar levels, blood pressure, cholesterol and hormones, according to Laux.

Blueberries also contain a compound called pterostilbene, which has been shown to reduce tumor growth.

Treatment will attempt to remove and reduce tumor growths, and is best performed as early as possible to catch the tumors before they spread.

Researchers will investigate how signaling pathways contribute to hemangiosarcoma growth, and if existing drugs can interrupt the process to reduce tumor growth and chemotherapy resistance.

Not exact matches

This recipe is full of chickpeas which help promote bone health, improve blood sugar levels in diabetics, improve blood pressure, promote heart health, reduce bad cholesterol, and reduce risks of cancer and decreases tumor growth rates.

Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).

They cross the blood - brain / blood - tumor barrier, and accumulate within brain tumor sites, where they target oncogenes, regulate cell growth and differentiation, reduce tumor burden and prolong survival in our mouse models.»

The researchers took this discovery and, in an animal model, identified a drug that is able to re-activate those immune cells and reduce brain tumor growth, thereby increasing the lifespan of mice two to three times.

With these in vitro test methods, the KU researchers have shown that anti-CD44s antibody can reduce pancreatic cancer cell growth, metastasis and ability of the tumors to recur after radiation therapy.

«Ionizing radiation found to soften tumor cell microenvironment: When irradiated, less stiff extracellular matrices reduced cancer growth and migration, bolstering the case to further understand fractionated radiation therapy.»

By contrast, when the team treated the mice with radiation plus a CCL2 - blocking antibody, the tumors» recruitment of monocytes and macrophages was sharply reduced, and the tumor growth was slowed more dramatically.

Together, they also investigated the consequences of mTOR inhibitors, existing cancer drugs aimed at reducing the growth of tumors.

The team's recent study in mice has found that the treatment reduced the mass of ovarian cancer tumors and was more effective at suppressing tumor growth than chemotherapy.

For several years already, it is well known that tumor growth can be reduced by suppressing autophagy in cancer cells.

When the researchers reduced the amount of IL13RA2 expression in the cancer cells, they found that the tumor growth was significantly slower in models.

Loeb points out that much of the concern over cancer risk is that, as part of standard therapy for advanced prostate cancer, tumor growth is decreased by drugs that drastically reduce rather than increase male hormones.

By blocking these in lung endothelial cells, the researchers were able to slow lung tumor growth in mice and also reduce the spread of metastatic tumors.

By using molecular genetic tools to reduce the amount of PC in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.

By deleting the gene that expresses p300, the researchers safely reduced Treg function and limited tumor growth in mice.

They confirmed this by showing that tumor growth was reduced in mice treated with an antibody drug that targets TIM - 3 and the chemotherapy agent paclitaxel, as compared to treatment with paclitaxel alone.

The scientists discovered that TRPV1, once activated by the EGFR, initiates a direct negative feedback on the EGFR, dampening the latter to reduce the risk of unwanted growth and intestinal tumor development.

Low doses of aspirin, an anti-platelet drug, have been shown to reduce the risk of some types of gastrointestinal cancers, but the process by which aspirin hampers tumor growth has been unclear.

To test this, researchers inhibited the ability of Runx2 to be phosphorylated in cancer cells and found that tumor growth was reduced.