Sentences with phrase «reduced tumor growth in»

Clinical trials lasting from one month to one year reported that consuming 25 grams of ground flaxseed daily reduced tumor growth in women with breast cancer and decreased breast cancer risk in younger women.

Importantly, while using rosiglitazone in conjunction with targeted therapy reduced tumor growth in both young and aged pre-clinical models, using rosiglitazone alone accelerated tumor growth in young models, while inhibiting it in aged ones.

Finally, they were also able to reduce tumor growth in their first in vivo xenograft analysis.

Not exact matches

This recipe is full of chickpeas which help promote bone health, improve blood sugar levels in diabetics, improve blood pressure, promote heart health, reduce bad cholesterol, and reduce risks of cancer and decreases tumor growth rates.

The results, published in Nutrition Research in 1988, showed reduced tumor growth rates in animals receiving phytic acid, but not in a control group.

They cross the blood - brain / blood - tumor barrier, and accumulate within brain tumor sites, where they target oncogenes, regulate cell growth and differentiation, reduce tumor burden and prolong survival in our mouse models.»

The researchers took this discovery and, in an animal model, identified a drug that is able to re-activate those immune cells and reduce brain tumor growth, thereby increasing the lifespan of mice two to three times.

With these in vitro test methods, the KU researchers have shown that anti-CD44s antibody can reduce pancreatic cancer cell growth, metastasis and ability of the tumors to recur after radiation therapy.

The team's recent study in mice has found that the treatment reduced the mass of ovarian cancer tumors and was more effective at suppressing tumor growth than chemotherapy.

For several years already, it is well known that tumor growth can be reduced by suppressing autophagy in cancer cells.

When the researchers reduced the amount of IL13RA2 expression in the cancer cells, they found that the tumor growth was significantly slower in models.

By blocking these in lung endothelial cells, the researchers were able to slow lung tumor growth in mice and also reduce the spread of metastatic tumors.

By using molecular genetic tools to reduce the amount of PC in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.

By deleting the gene that expresses p300, the researchers safely reduced Treg function and limited tumor growth in mice.

They confirmed this by showing that tumor growth was reduced in mice treated with an antibody drug that targets TIM - 3 and the chemotherapy agent paclitaxel, as compared to treatment with paclitaxel alone.

To test this, researchers inhibited the ability of Runx2 to be phosphorylated in cancer cells and found that tumor growth was reduced.

In particular, the combination reduced tumor growth and angiogenesis, the process by which tumors recruit blood vessels to feed their expansion.

«We also found that methylnaltrexone reduced tumor growth and spread in several cancer models,» Singleton said.

They also tested Rapalink's ability to inhibit tumor growth in animal experiments, and found that it reduced the size of tumors that were resistant to first - or second - generation mTOR inhibitors.

The researchers then turned to a JAK2 - specific inhibitor now known as BSK805 which markedly reduced TNBC tumor growth in mice when paired with chemotherapy.

In the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in OncotargeIn the treated mice, the treatment strongly reduced the tumor growth with no toxicity to the mice, reports the study in Oncotargein Oncotarget.

These compounds have been shown to inhibit cancer cell growth, induce cancer cell apoptosis, and reduce tumor volume in mice (14, 15, 16, 17).

The importance of stromal POSTN was also demonstrated in another study in which orthotopic inoculation of gastric cancer cells into Rag2 − / −; Postn − / − mice reduced tumor size, decreased invasiveness, and decreased growth compared to Rag2 − / −; Postn + / + mice (Kikuchi et al., 2014).

URBANA, Ill. — Years of research in University of Illinois scientist John Erdman's laboratory have demonstrated that lycopene, the bioactive red pigment found in tomatoes, reduces growth of prostate tumors in a variety of animal models.

Knowing that insulin can stimulate the growth of blood vessels, «our expectation was that knocking out insulin signaling in these cells might slow the growth of blood vessels and reduce tumor formation in these mice,» Rask - Madsen says.

The conjugate, which they named «chemocoxib A,» reduced growth of COX - 2 positive tumors in mice by 50 percent, but didn't have any effect on tumors that didn't express the enzyme.

In some of the children, the drugs blocked tumor growth; in others, they reduced tumor sizIn some of the children, the drugs blocked tumor growth; in others, they reduced tumor sizin others, they reduced tumor size.

: Therapy with MIA - 602 significantly reduced tumor growth and enhanced the efficacy of doxorubicin in both cell lines.

Combination therapy resulted in significantly reduced growth compared to controls (P < 0.001), and tumors treated with MIA - 602 (P < 0.05) or doxorubicin (P < 0.001)(figure 1b).

Conversely, blocking CXCR4 / CXCL12 pathway in triple - negative (TN) BC does not reduce tumor growth, and can even increase metastatic spread.

Results: Therapy with MIA - 602 significantly reduced tumor growth and enhanced the efficacy of doxorubicin in both cell lines.

Furthermore, in COX - 2 deficient mice a decrease in VEGF, and both reduced angiogenesis and tumor growth were observed [40].

Furthermore, we found that human IL - 15 mediated insulin - like growth factor - 1 production in CD215 + myeloid cells and blocking IGF - 1 reduced the tumor - promoting effect of IL - 15.

But no enhanced or reduced tumor growth was observed in mice when human IL - 15 was used.

Recent studies have shown that curcumin can reduce growth of new blood vessels in tumors and metastasis and basically help kill off cancerous cells.

Lycopene, which is found in tomatoes, has actually been shown in some studies to reduce tumor growth, and can help protect against lung, stomach, colon, oral, breast AND cervical cancers!

Possible reduction in certain types of cancer: «It appears to work primarily by blocking the growth and metastatic spread of tumors, controlling the cell cycle, and by reducing inflammation.»

● Protect cells, slow tumor growth and reduce side effects of chemotherapy treatment in cancer patients.

In laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animalIn laboratory studies, the turmeric (curcumin) herb reduced the growth of cancerous cells and inhibited the growth of tumors in the laboratory test animalin the laboratory test animals.

In some cases, a person with a tumor in the pituitary gland could have reduced human growth hormone production, but the reverse could also be truIn some cases, a person with a tumor in the pituitary gland could have reduced human growth hormone production, but the reverse could also be truin the pituitary gland could have reduced human growth hormone production, but the reverse could also be true.

Dr. Mechoulam: There are several groups that have found it effective in reducing tumor growth.

This mineral has been known to reduce inflammation, decrease tumor growth, and has the ability to stimulate the production of killer T - cells — which improves immune function in response to infections.

: The aforementioned catechins, known as a potent antioxidants, contained in the matcha leaf may play a major role in preventing and reducing the risk of cancer as they activate detoxification enzymes in the body and help improve immune system function, which can repair damaged cells and prohibit growth of tumors.

Researchers report that curcumin reduces all pro-inflammatory molecules in cartilage cells and in membranes that line the joints, among them tumor necrosis factor — which destroys joint cartilage — and vascular endothelial growth factor, which promotes excessive growth of blood vessels in inflamed joints.

Contained in the juice of a pineapple are two digestive enzymes which help thin the blood in a fashion similar to the drugs aspirin and Coumadin, helps reduce pain and inflammation, and may help slow tumor cell growth.

Multiple studies in laboratory's show that curcumin can reduce the growth of tumors, the spreading of cancer, and contribute to overall cancer cell death.

They evaluated graviola extract and found that it contains compounds that play a role in regulating the metabolism, survival and growth of cancer cells, shrinking tumors and reducing cancerous cells» ability to grow and spread.

Cancer: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply [45].

: In 1914, Nobel Laureate Payton Rous, Father of the tumor virus, suggested restricted food intake reduced tumor growth by reducing tumor blood supply

A couple of studies have shown that eating flaxseeds may reduce markers of tumor growth in women with breast cancer, and may also reduce cancer risk (10, 11, 12).