Sentences with phrase «reduces cell death»

N - Acetylcysteine Amide (NACA) Reduces Cell Death after Oxidative Stress in a Porcine Embryonic Kidney Cell Line
They performed an experiment in which they gave back SP9 to the diseased cells and found that returning this protein to the diseased neurons reduced cell death to levels similar to healthy control cells.
Overall, the presence of B lymphocytes was associated with increased tissue proliferation, reduced cell death and a more supportive environment for wound healing.
The pathway then uses the tumor's metabolism to break down glucose and use its energy to reduce cell death and maintain proliferation.
Preclinical data indicates that these cells promote blood vessel growth, modulate inflammation and reduce cell death.

Not exact matches

There it directly targeted multiple oncogenes at once, increasing cancer cell death and reducing cancer cell growth.
In the present study conducted at IDOR in conjunction with UFRJ, the research team observed that ZIKV infects human - derived iPS neural cells, neurospheres and cerebral organoids causing cell death, malformations and reducing growth by 40 %.
«Damaging consequences of Zika virus infection in human minibrains: Zika virus reduces growth, induces cell death, malformations in human neurospheres, brain organoids.»
After using the enzyme to cause rod cell death in the fish, the researchers added the anti-inflammatory drug to the water to reduce microglia reactivity.
Two other critical features of NASH, inflammation and cell death, were also reduced when TAZ was turned off.
After 10 days of age, the manipulations reduced the distance flies could climb up tubes and the alterations caused older flies to have signs of neurodegeneration, including higher than normal levels of brain cell death and degradation.
The research team found that when a particular mitochondrial fission protein (GTPase dynamin - related protein - 1 — Drp1) was blocked using either gene - therapy or a chemical approach in experimental models of PD in mice, it reduced both cell death and the deficits in dopamine release — effectively reversing the PD process.
This reduced ER function results in ER stress and contributes to the death of beta cells and the insulin insufficiency that is characteristic of T1D.
If the compound identified in this study successfully reduces tissue death and improves recovery in further experiments, it could lead to new approaches for preserving brain cells after an ischemic stroke,» said Francesca Bosetti, Ph.D., Pharm.D., program director at the NIH's National Institute of Neurological Disorders and Stroke (NINDS).
«Blocking excessive division of cell powerhouses reduces liver cell death in cholestasis.»
Also, in both cell culture and a mouse model of the condition, blocking the excessive splintering reduced production of reactive oxygen species, a potentially harmful byproduct of metabolism, as well as cell death.
They assessed gene activity at time points known to correspond with key phases of disease: the «induction phase,» the time before the peak level of photoreceptor cell death; the «execution phase,» when the highest rates of photoreceptor cell death occur; and the «chronic phase,» during which photoreceptor cell death continues at somewhat reduced levels.
The collaborative work conducted by the Terskikh and Muotri labs showed the drug decreased viral levels, reduced neural cell death and limited the amount of virus transmitted to babies.
Combining a cancer therapy with a second drug therapy that helps suppress tumour blood vessels found in cancer cells can help to significantly reduce the spread of breast cancer tumours while also causing cancer cell death.
«Because it helps cells avoid death, TGF - β can reduce the negative impact that the metastatic process has in the cancer cells,» Lopez - Diaz says.
That, in turn, reduces the cells» ability to resist cell death through a process called anoikis.
The unique blend of stem and regenerative cells found in your adipose tissue have the capability to reduce inflammation and prevent continued cell death while repairing / replacing damaged tissue.
Same thing in giant turtles who normoglycemic or hypoglycemic for their entire life; Centenarians have reduced blood glucose levels and reduced blood glucose increase over the years, their blood glucose is monotonic plateau, where as elders dying below 80s show blood glucose rise each decade until their death, their pancreatic Beta cells can't secrete enough insulin and they are mildly pre - diabetic / insulin resistant.
If he can determine how to speed up engulfment of dead tumor cells from brain tissue, it is his hope to reduce the harmful inflammation that causes death of surrounding neurons.
In addition, estrogen use may decrease the risk of developing glaucoma, prevent retinal ganglion cell death, reduce intraocular pressure and preserve visual acuity.
The Zika virus is known to negatively impact the growth of fetal brains and a group of researchers publishing in the journal Cell Stem Cell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatCell Stem Cell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatCell have investigated the effect of Zika on the adult brain reporting that infection can lead to cell death and reduced proliferatcell death and reduced proliferation.
Inhibition of Notch signaling reduces proliferation of stem cells, induces cell death, and down - regulates non-canonical Wnt5a, suggesting that the Notch pathway contributes to maintenance and motility of the stem cells.
His studies, ranging from molecular experiments to clinical trials, have generated comprehensive evidence for the efficacy of omega - 3 in preventing cardiac sudden death and established the mechanism by which omega - 3 fatty acids can reduce cardiac arrhythmia by interacting with membrane ion channels and stabilizing the electrical activity of heart cells.
The drugs reduce pain and inflammation by inhibiting the cyclooxygenase (COX) enzymes, which are involved not only with inflammation but also with certain processes involved in cancer, such as blood supply to the tumor and programmed cell death (known as apoptosis).
Finally the soy isoflavone genistein reduces DNA synthesis in the brain, reducing the birth of new brain cells and promoting apoptosis and cell death.
While various studies have shown that fluoride reduces the incidence of dental cavities and tooth decay, fluoride is an endocrine disruptor and studies confirm that fluoride is directly toxic to thyroid cells and causes thyroid cell death, suppressing thyroid activity.
In men having prostate cancer, a low fat diet supplemented with 30 grams of ground flaxseed reduces serum testosterone by 15 %, slows down the growth rate of cancer cells, and increases the death rate of cancer cells.
Based on our understanding of human physiology and longevity, coffee reduces your risk of death by helping your cells produce energy, increasing your metabolism, and therefore improving thyroid function.
Studies suggest that flax may reduce the growth of abnormal cells and increase apoptosis (programmed death) of cancer cells in breast tissue (1, 2, 3).
This way of eating has been shown to reduce inflammation, prevent oxidative stress and limit cell death in both Alzheimer's and Parkinson's disease.
As with the ketogenic diet, caloric restriction also reduces oxidative stress, reduces inflammation and inhibits cell death.
One study found strawberry phenolic compounds to reduce oxidative stress and cell death and to have protective effects on neuronal cells.
Multiple studies in laboratory's show that curcumin can reduce the growth of tumors, the spreading of cancer, and contribute to overall cancer cell death.
Significant cell death was observed as well as reduced IGF - 1 levels in the blood.
This disease - fighting nutrient can slow the growth and development of new blood vessels that nourish tumors, increase a type of programmed cancer cell death known as apoptosis and reduce the proliferation of new cancer cells.
It also helped protect against oxidative damage that leads to brain cell death, and reduced injury to brain endothelial cells in mice with high - fat diets.
This study showed that theanine can reduce neuronal cell death in brain cortex and hippocampus.
Researchers say ibuprofen can reduce blood flow to the cochlea, the auditory portion of the inner ear, which could result in cellular damage and cell death.
The good news is that replenishing NAD + to cells can restore DNA repair and prevent cell death under stress.26, 29 In two different animal models of neurodegenerative disease, increasing cellular NAD + reduced the severity of the disorder, normalized neuromuscular function, delayed memory loss, and extended lifespan.30
Here's a quote: «Lactoferrin: Lactoferrin found in foods such as yogurt and kefir will stimulate new bone growth while preventing further breakdown of existing bone tissue, lactoferrin enhances both the growth and the activity of osteoblasts (the cells that build bone), and reduces the rate of bone cell death by 50 to 70 percent and decreases the development of osteoclasts, the cells responsible for breaking down bone.»
Clinical and laboratory research has shown that certain herbs can support normal function of the liver, kidneys, heart and immune system; reduce inflammation and improve blood flow through damaged tissues; promote the differentiation, aging and death of tumor cells; and reduce pain.
Managing the destructive chain reaction (spinal cord injuries immediately set off a sequence of secondary injuries including: inflammation, reduced blood flow and cell death)
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