Another Reason to Get Plenty of Fiber Fiber helps prevent viscous (thick) bile by reducing cholesterol absorption in the intestines, and also
reducing cholesterol synthesis.
Kahn and his team suspected that
reduced cholesterol synthesis interferes with brain synapses.
Not exact matches
MicroRNAs that
reduce cholesterol export from cells are encoded in the same genes that increase
cholesterol synthesis.
Despite this possibility, mevinolin, the active ingredient in red yeast rice, is capable of
reducing 7 - dehydrocholesterol levels, 22 and simvistatin (Zocor) not only inhibits the
synthesis of mevalonate but also enhances the conversion of 7 - dehydrocholesterol to
cholesterol by increasing the expression of 7 - DHCR.23 Simvistatin thereby hits the pool of 7 - dehydrocholesterol with a double - whammy, both decreasing its
synthesis and increasing its degradation.
Muscle cells ordinarily contain significant levels of glutathione, and its depletion leads to mitochondrial damage.23 Patients undergoing surgical trauma have been found to exhibit
reduced glutathione levels in their skeletal muscles.21 It is tempting to speculate that
cholesterol sulfate provides the sulfur needed for glutathione
synthesis, so that the deficiency would be explained by the
reduced availability of
cholesterol following the immune system's heightened response to surgical trauma.