Not exact matches
The study also suggests that the
reduction in volume drives the
reduction in brain activity,» says doctoral student Kristoffer NT Månsson, who led the study together with Linköping colleague Gerhard Andersson and researchers from the Karolinska Institutet, Uppsala University, Umeå University and Stockholm University.
Some 30 animals have been domesticated, he notes, and
in the process every one of them has lost
brain volume — typically a 10 to 15 percent
reduction compared with their wild progenitors.
Specifically, compared with controls, marijuana abusers had significantly attenuated behavioral («self - reports» for high, drug effects, anxiety, and restlessness), cardiovascular (pulse rate and diastolic blood pressure), and
brain DA [reduced decreases
in distribution
volumes (DVs) of [11C] raclopride, although normal
reductions in striatal nondisplaceable binding potential (BPND)-RSB- responses to MP.
They found
reductions in the
volume of gray matter
in multiple regions of the
brains of children with OSA.
The condition has been linked to widespread
reduction in the
brain's tissue
volume but it was observed that certain
brain regions show a subtle increase
in tissue over time.
MRI volumetric analysis detected significant
reduction of
volume of whole
brain, striatum and hippocampus at 24 weeks of age
in the knock - down mice.
There are precedents that parallel our apparently paradoxical finding.36, 37
In a β - amyloid immunization trial among those with probable Alzheimer disease, immunization led to significant clinical benefit, reduced β - amyloid load, and reduced brain volume.36 The investigators hypothesized that removal of β - amyloid and / or other protein constituents from brain tissue may have caused cerebral fluid shifts, resulting in brain volume reductions on magnetic resonance imagin
In a β - amyloid immunization trial among those with probable Alzheimer disease, immunization led to significant clinical benefit, reduced β - amyloid load, and reduced
brain volume.36 The investigators hypothesized that removal of β - amyloid and / or other protein constituents from
brain tissue may have caused cerebral fluid shifts, resulting
in brain volume reductions on magnetic resonance imagin
in brain volume reductions on magnetic resonance imaging.
Although reduced
brain volumes are commonly associated with impaired function, 35 the groups who improved cognitive executive function and muscular function
in our study also had
brain volume reductions.
It has been proposed that the
volume mismatch between the CCF and
brain parenchyma
in CKCS can be explained by impaired occipital bone development and the consequent
reduction in CCF
volume [5], [16], [21].
Specifically, exposure to prenatal and / or postnatal stress is associated with increased basal and stress - induced responsiveness of the hypothalamic pituitary adrenal axis, increased central corticotropin - releasing hormone and norepinephrine drive, decreased γ - aminobutyric acid / benzodiazepine functioning, multiple alterations
in the serotonergic system, and
reduction in hippocampal
volume, a
brain structure vulnerable to the neurotoxic effects of stress - induced elevations
in circulating glucocorticoids (e.g., cortisol) and amino acids (e.g., glutamate).
[9] There is evidence to support the claim that stress causes
brain changes, such as
reductions in hippocampal
volume.9 Research has also indicated that recurrent episodes of MDD might cause
reductions in hippocampal
volume.