About 720,000 people experience a heart attack annually in the United States, which means that hundreds of thousands of people each year could benefit from a therapy to repair and
regenerate damaged heart muscle.
Not exact matches
On average the transplanted stem cells
regenerated 40 percent of the
damaged heart tissue, said Dr. Michael Laflamme, UW assistant professor of pathology, whose team was principally responsible for generating the replacement
heart muscle cells.
«Stem cell therapy
regenerates heart muscle damaged from
heart attacks in primates.»
Together, the teams of Drs. Srivastava and Ding are confident that they will soon find a way to eliminate the need for genes entirely, thus using only a cocktail of small molecules to generate beating
heart muscle and
regenerating damaged hearts.
Dr. Srivastava's lab has leveraged the body of knowledge from cardiac developmental biology to reprogram non-
muscle cells in the mouse
heart directly into cells that function like
heart muscle cells, effectively
regenerating heart muscle after
damage.