The brains of aging humans are prone to neurodegenerative disorders and we are unable to counteract neuronal loss by
regenerating lost cells.
Not exact matches
When Pax7 is missing or reduced, the satellite
cells undergo premature differentiation, or
lose their stem properties and their ability to
regenerate injured muscles.
«Novel drug candidate
regenerates pancreatic
cells lost in diabetes.»
Stem
cells, which have to divide regularly to
regenerate tissues with new
cells, can produce telomerase, but not the amount required to counteract the shortening of telomeres that accumulates with aging: over time, the tissues have fewer fresh
cells and they
lose their regenerative capacity.
Previous research conducted by Dr. Badylak's team suggested that ECM also could be used to
regenerate lost muscle by placing the material in the injury site where it signals the body to recruit stem and other progenitor
cells to rebuild healthy tissue.
That's one of the distinguishing features between stem
cell therapy, which is to
regenerate lost tissue, and gene therapy, which at the moment is there to sustain
cells that would otherwise die.»
One idea is that if we could harness the very stem
cells that are in the noses of people who are
losing smell, maybe we can figure out a way to restore function, by getting them to
regenerate the
cells that are
lost.»
Researchers at the Whitehead Institute in Cambridge, Massachusetts, US, have now found that adult stem
cells in bone marrow gradually
lose their ability to
regenerate without their normal complement of membrane - bound prions.
Not only did the team's results point to the power of chemical reprogramming to generate a complete transformation, they also revealed that this type of regenerative therapy could use the patient's own
cells to
regenerate the
cells lost to disease.
But in a striking finding, all
regenerated heart muscle
cells glowed green, indicating that well established cardiomyocytes remaining after injury had likely regressed to a more «youthful» state, started dividing again to replenish
lost cells, and then matured a second time into new heart muscle.
The hope, in the wake of Yamanaka's discovery, was that iPS
cells could be a controversy - free alternative, conferring on humans a newtlike ability to
regenerate lost or diseased tissue.
A central premise of regenerative medicine is that, to discover how we can
regenerate lost motor neurons or insulin - secreting pancreatic
cells, it is necessary to understand how such
cells develop in the first place.
This research lays the groundwork for one day being able to
regenerate lost or damaged
cells in the body with a drug.
The research lays the groundwork for one day being able to
regenerate lost or damaged
cells with pharmaceutical drugs.
Stem
cells, which have to divide regularly to
regenerate tissues with new
cells, can produce telomerase, but not the amount required to counteract the shortening of telomeres that accumulates with ageing: over time, the tissues have fewer fresh
cells and they
lose their regenerative capacity.
The first part of this is to generate — or
regenerate —
cells that sense glucose and produce insulin that might ultimately be used to replace the beta
cells lost as both type 1 and 2 diabetes progresses.
You found this webpage because your veterinarian told you that your pet's liver is no long able to
regenerate its
lost liver
cells (hepatocytes).
Many invertebrates can
regenerate body parts like
lost tails or arms, but crayfish naturally turn blood
cells into brain
cells.