Tobias Langenberg (Brand, MPG)-- «Neuromeric organization of the midbrain hindbrain boundary
region in zebrafish» (2004)
Surprisingly, the researchers found a similar bimodal 3 - dimensional chromatin architecture in the Hoxd gene
region in zebrafish embryos.
Not exact matches
Companies
in the
region that have announced staff cuts include Oxford - based Summit Corporation, a
zebrafish genomics specialist; Alizyme of Cambridge, which is developing treatments for gastrointestinal diseases; and Silence Therapeutics of London, an siRNA company.
Functional analyses indicate that MFSD12 encodes a lysosomal protein that affects melanogenesis
in zebrafish and mice, and that mutations
in melanocyte - specific regulatory
regions near DDB1 / TMEM138 correlate with expression of ultraviolet response genes under selection
in Eurasians.
The results from McCammon's initial screen with
zebrafish indicate that two genes
in the 16p11.2
region could be key for brain development: fam57ba and doc2a.
Below is a short video of the current system showing the anatomically correct
zebrafish brain
regions in 3D.
We have found that some of these variants are located
in genome
regions conserved down to the
zebrafish, and surrounded by the same neighborhood of genes as
in the human genome.