But difficulties in pinning down susceptibility genes in
those regions led geneticist Matthew State at Yale University Medical School to take a different approach.
Not exact matches
Researchers thought they were hot on the trail of «gay genes» in 1993, when a team
led by
geneticist Dean Hamer of the National Cancer Institute reported in Science that one or more genes for homosexuality had to reside on Xq28, a large
region on the X chromosome.
Researchers
led by Kári Stefánsson, a
geneticist with deCODE Genetics in Reykjavik, Iceland, identified 27 such
regions, and the other two groups,
led by
geneticist Timothy Frayling at Peninsula Medical School in Exeter in the U.K., and Joel Hirschhorn, a
geneticist at the Broad Institute in Cambridge, Massachusetts, spotted 20 and 10
regions, respectively.
The team,
led by human
geneticist Koh - ichiro Yoshiura of Nagasaki University, had previously localized the earwax gene to a
region on human chromosome 16.
«There was a major demographic transformation in India from a
region where mixture was pervasive to one in which it is very rare because of a shift to endogamy,» says
lead author Priya Moorjani, a
geneticist at Harvard Medical School.