Sentences with phrase «regulate cell function»

As I mentioned above, magnesium works in tandem with calcium to regulate cell function in muscle contraction and neurotransmitter release.

Palovarotene is a retinoic acid receptor (RAR) agonist, a molecule that binds a cell membrane receptor to trigger molecular events that regulate cell function.

MAPK regulates cell functions, including proliferation, gene expression, differentiation, cell division and a form of cell suicide known as apoptosis.

Vital functions of an organism occur within cells, and all cells contain the hereditary information necessary for regulating cell functions and for transmitting information to the next generation of cells.

Focal adhesions transmit tensile stresses from the extracellular space to the cytoskeleton, thereby converting force cues into biochemical signals that regulate cell functions [6].....

In order to know what parts of the code are used to regulate cell functions and create traits the RNA from the organism needs to be sequenced.

Regular exercise not only helps you breathe away excess fat, but it also better sensitizes and regulates cell function to be fat burning rather than fat promoting.

In order to know what parts of the code are used to regulate cell functions and create traits the RNA from the organism needs to be sequenced.

Not exact matches

Sodium plays a role in your critical body functions by regulating the movement of water in and out of your cells.

Coconut oil provides many benefits including the ability to regulate blood sugar and hormone levels, boost thyroid function, fuel the human body's metabolic demands and provide healing support to cells, tissue and organs.

The high fibre content is excellent for regulating bowel function, cutting cholesterol, removing toxins from the body and since this bean fibre binds to fat cells it flushes them from the body too - got ta luv that!

Peptides can bind to targets on a cell (usually receptors or enzymes that are themselves proteins) and so regulate cellular functions such as nutrient uptake or communication between cells.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

Based on this work, they decided to investigate whether miR -17-92 regulates T - and B - cell differentiation and function in the development of cGVHD.

In the meantime, the MUSC team, led by Yu, will continue their work and try to extend the current findings by investigating how other miRs may be involved in regulating T - and B - cell function during allogeneic BMT.

Researchers still don't know how this range corresponds to their versatile functions, but being more like a string than like a lump with keyholes means that a protein can make many contacts with other molecules to regulate the network of signals that drives the cell.

The two genes implicated — GNAQ and GNA11 — code for proteins (known as G proteins) that normally function as molecular on - off switches, regulating the passage of information from the outside to the inside of a cell.

These play a key role in controlling gene expression and, thereby help regulate the cell's development, growth and function.

«This evidence suggests that the DNA timing mechanism is highly conserved, and it is possible that other time - critical functions related to the cell cycle may be regulated in a similar way.

«Our study demonstrates that ANG regulates critical functions of both clinically - relevant cell types.»

First author Kim Martinod, a graduate student in the Immunology Graduate Program at the Harvard University Medical School, found that, in response to vein constriction, these «rescued» mice now could function normally, forming clots as efficiently as mice with a functioning Pad4 gene, demonstrating that the Pad4 gene did produce a functioning PAD4 enzyme in these white blood cells to regulate blood clotting.

While analyzing molecules excreted by TRPV1 cells in search of anything that might be itch - specific, Hoon and his colleagues came across a small group of the neurons that produce natriuretic polypeptide b (Nppb), a hormone that regulates heart function and can also act as a neurotransmitter.

RNA, like DNA, encodes information for cell functions, but RNA can also fold up and perform tasks, like signaling, regulating or catalyzing reactions.

This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time that dopamine deficiencies can affect a variety of behavioral and physiological functions regulated in the prefrontal cortex.

Changes to the properties of the lipid bilayer component of the cell membrane can alter the function of proteins embedded in the membrane — proteins that regulate critical functions such as transport of materials in and out of the cell and communication with other cells.

Disease processes often begin with mutations in the transcription factor, or in the DNA they bind to inside the nucleus of cells to regulate the complex interplay of genes needed for a healthy functioning body.

An extensive database identifying immune traits, such as how immune cell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal Ccell function is regulated at the genetic level in healthy people, is reported by researchers from the National Institutes of Health (NIH) and their collaborators in the journal CellCell.

BPA mimics the actions of the hormone estradiol — a natural hormone that can regulate beta cell function and provoke insulin resistance.

When functioning properly, OTULIN regulates the development of new blood vessels and mobilization of cells and proteins to fight infection.

Research from Rutgers Cancer Institute of New Jersey shows that the RUNX2 protein, which regulates the transcription of genetic messages responsible for the different functions of cells, may play a role in melanoma cell growth and spread and could serve as a therapeutic target for the disease.

Even a small number of functioning, insulin - producing cells can restore hypoglycemic awareness, although transplant recipients may need to continue taking insulin to fully regulate blood glucose levels.

The body relies on cells to process and store energy, and changes in genes that regulate these functions can cause an imbalance that leads to excessive energy storage and weight gain.

Insulin sensitivity refers to insulin's ability to efficiently respond to and regulate glucose in the blood, so that our cells can use it for energy and other functions.

Augmenting and regulating telomerase function will have to be performed with precision, walking a narrow line between cell rejuvenation and a heightened risk for cancer development.

The middle layers also proved to have their own functions, rather than serving as mere transition zones: The researchers found, for example, that cells in these layers manufacture the hormone hepcidin, which regulates iron levels in the blood.

Ozcan realized that inflammation might help when he noticed that in obese diabetic mice, XBP - 1s failed to enter the cell nucleus, where insulin function is regulated.

«These results represent a significant advance in our understanding of how commensal microbes can regulate host intestinal immune responses and suggest that the identification of downstream targets in macrophages and dendritic cells along the GM - CSF axis can help the rationale design of novel strategies for the treatment of IBD patients with defective GM - CSF function,» explained Dr. Merad.

«These new results from Dr. Liu and his colleagues also extend beyond understanding the function of an anti-sense RNA in the fine tuning of a cell's daily rhythm; they provide an example of the means by which anti-sense transcription likely regulates other key molecular and physiological processes in cells and organisms.»

Molecular analysis showed that heart cells in affected animals were poorly developed and had mitochondrial defects, indicating that Sap130 - Pcdha9 gene interactions play a crucial role not only in heart development but also in regulating metabolic function of the cardiac muscle.

While many protein factors are known to subtly regulate the function of T cells, David Munn and Andrew Mellor of the Medical College of Georgia in Augusta suggest that the fetus uses a cruder method to alter T cells» behaviour: starvation.

Obtaining detailed insights into their three - dimensional shape will not only help to understand how they function but also how this function is regulated in the cell.

Along with intestinal stem cells, the team identified differentiated nutrient - digesting and absorbing enterocytes, mucus - producing Goblet cells, hormone - secreting enteroendocrine cells, and microbiome - regulating and sensing Paneth cells, and they performed a series of assays that confirmed their functions.

Stowers researchers discovered that megakaryocytes directly regulate the function of murine hematopoietic stem cells — adult stem cells that form blood and immune cells and that constantly renew the body's blood supply.

Although the main function of gut endocrine cells is to regulate digestion, the Duke researchers found these cells also have nerve - like properties.

«We want to know what the basic function of GATA - 3 in regulating cell biology is, although it has been shown that GATA - 3 is important for the function of CD4 + T cell type to clear extracellular parasites,» said Yisong Wan, PhD, assistant professor of microbiology and immunology at the UNC School of Medicine and member of UNC Lineberger Comprehensive Cancer Center.

Northwestern Medicine scientists have discovered that two key cellular structures, called mitochondria and lysosomes, come into direct contact with each other in the cell to regulate their respective functions.

In its active form, it functions to regulate levels of heparan sulfate, a kind of generic cell membrane receptor.

According to Dr. Bleich and his co-investigators, «Epithelial barrier function is predominantly dependent on tight junction proteins, which regulate transport into and between cells.

Eukaryotic cells are compartmentalized by membranes, whose shape and dynamics are precisely regulated to maintain their correct functions.

The receptor also regulates DHA retention and conservation in cells in the eye and is necessary for photoreceptor cell function.