Later work suggested a more nuanced role for it, Ben - David says, but the overall hypothesis remained that the genes helped
regulate embryo development.
Not exact matches
Studying these rare diseases «can open a new way to understand the imprinting phenomenon, to see how, in the beginning of the
development of the
embryo, the
embryo answers to stimuli» that
regulate how its genes behave, says Giovanni Battista Ferrero, a pediatrician at the University of Turin in Italy.
«The most intriguing of these genes is FGFRL1, which has a cluster of amino acid substitutions unique to giraffe that are located in the part of the protein that binds fibroblast growth factors — a family of regulators involved in
regulating many processes including
embryo development,» Cavener said.
The researchers determined that the Sip1 protein is responsible specifically for the
development of
embryos and that it is
regulated via the pH value rather than temperature.
In particular, the research identified several genes
regulated by methylation in the egg that are involved in cell adhesion and migration — both vital properties for cells of the developing placenta in establishing connections with maternal tissues to support
embryo development.
Lanner is attempting to edit genes in human
embryos to learn more about how the genes
regulate early embryonic
development.