Sentences with phrase «regulate key genes»

After being eaten with food, the miRNAs might enter the bee's gut and spread throughout the rest of the body, where they could help regulate key genes, the scientists say.
Moffitt researchers want to develop a fast, cost - effective blood test that can accurately differentiate low - risk IPMNs that can be monitored from high - risk IPMNs that need to be surgically removed by studying microRNAs (miRNAs), a class of small molecules that regulate key genes involved in the development and progression of cancer.
According to Beg, NF - κB proteins regulate key genes involved in immune response, inflammation, cell death and cell growth.

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However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.
Together, these experiments show that the PERIOD3 gene likely plays a key role in regulating the sleep - wake cycle, influencing mood and regulating the relationship between depression and seasonal changes in light availability, the team reports today in the Proceedings of the National Academy of Sciences.
The key differences they uncovered lay within regions of the gene that regulate how many receptors are made.
A decade of post-genomic biology has also focused new attention on the regions outside protein - coding genes, many of which are likely to have key functions, through regulating the expression of protein - coding genes and by making a slew of non-coding RNA molecules.
The researchers attached these entry keys to PNAs designed to shut down expression of a test gene — the galanin receptor gene, which binds a protein, galanin, that helps regulate everything from pain perception to food intake.
That enzyme regulates the way key learning and memory - related genes turn on and off during development.
These play a key role in controlling gene expression and, thereby help regulate the cell's development, growth and function.
In the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expression.
A key function of c - MYC is to regulate the transcription of numerous genes.
Interestingly, the let - 7 family of micro RNA affects several key genes that regulate glucose metabolism, called the PI3 / AKT / insulin pathway.»
Scientists have identified genes that are active during puberty, but most also have key functions in other basic processes, such as regulating fat.
Key proteins, produced and regulated by these important genes, activated a cascade of diverse, tissue - specific signals that led to regenerative organ growth.
Further, Shankman identified a key gene, Klf4, that appears to regulate these transitions of smooth muscle cells.
The lipoprotein transport system holds the key to understanding the mechanisms by which genes, diet, and hormones interact to regulate the plasma cholesterol level in man.
Howard Hughes Medical Institute (HHMI) scientists have profiled key features of the genetic material inside three types of brain cells and found vast differences in the patterns of chemical modifications that affect how the genes in each type of neuron are regulated.
They play a key part in regulating the activity of genes in many species, from yeast to humans Fewer than 10 years ago no one knew they existed
The HLA (human leukocyte antigen) is a system of genes responsible for regulating immune responses, and peptides are short chains of amino acids that play key roles in regulating the activities of other molecules.
Single - stranded, noncoding micro-ribonucleic acids (microRNAs), consisting of 18 - 23 nucleotides, play a key role in regulating gene expression.
MicroRNAs regulate gene expression and play key roles in many biological processes, such as cell death and metabolism.
Histone proteins are key building blocks of this architecture and contain crucial information that regulates our genes.
A variant in a region of the genome that is not coding for a protein can have a relatively large effect on a gene regulating bone health,» says Dr. Douglas Kiel, whose NIH - funded team at Hebrew SeniorLife and Harvard Medical School played a key role in the effort.
FoxO1 Deacetylation Regulates Thyroid Hormone - induced Transcription of Key Hepatic Gluconeogenic Genes.
PPI does not introduce any foreign genes into its products; rather it regulates the plant's own genes to increase or decrease expression of the genes responsible for key traits.
They discovered that extra chromosome 21 - a genetic state known as trisomy 21 - disturbs a key regulating gene called NRSF or REST, which in turn disturbs the cascade of other genes that control normal development at the embryonic stem cell stage.
In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological...
Through this packaging mechanism, researchers think that histone proteins are the key to regulating access to the genetic information by making different parts of the DNA accessible to factors that express the gene, so - called epigenetic regulation.
Previous research in mice showed that a protein called ASIC1a acts, indirectly, as a carbon dioxide sensor in the amygdala, a region in the brain key to the perception of danger and fear, and that the ASIC1a gene regulates carbon - dioxide induced anxiety.
Sirtuins are enzymes regulating the expression of genes that control the function of cells through key cellular signalling pathways.
The researchers discovered signaling networks and key genes regulated by the omega - 3 fatty acid DHA and also vitamin D3 which can help manage inflammation and greatly boost plaque clearance.
Curcumin activates PPAR (peroxisome proliferator - activator receptor) which is a group of key nuclear proteins that regulate gene expression and modulate sugar uptake and utilization in the bloodstream.
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