Not exact matches
The researchers found that the blond hair commonly seen in Northern Europeans is caused
by a
single change in the DNA that
regulates the expression of a
gene that encodes a protein called KITLG, also known as stem cell factor.
With the data provided
by the FLI researchers, scientists around the world may now set targeted mutations to investigate the relevance of
single genes for aging, in order to better understand
regulating mechanisms and, eventually, develop new approaches for therapy or prevention of aging - related diseases.
An enzyme encoded
by a
single gene, for example, can
regulate the synthesis of many different lipids.
Because of the
single mutation in GATA4, virtually the entire network of
genes regulated by GATA4 and TBX5 were disrupted, resulting in disease.
MicroRNAs, or miRNAs, are short,
single - stranded bits of RNA that
regulate the messenger RNA expressed
by genes to create a protein.