Sentences with phrase «regulated by proteins»

These cell activities are regulated by proteins normally found at the cell's membrane.

They found that the cell recycling machinery is regulated by a protein called WHAMM, and that interfering with this protein or actin polymerization itself severely inhibits the cell's ability to recycle misfolded proteins and damaged organelles via autophagy.

In addition, the research team discovered that the development of ILT3 in Treg cells is regulated by protein kinase CK2.

«These reserve stem cells that we had shown were important for the beneficial effects of calorie restriction, were repressing many pathways that are all known to be regulated by the protein complex mTOR, which is most well known as being a nutrient - sensing complex.»

«Our results show that the movement of mitochondria from stem cells to recipient cells is regulated by the protein Miro1 and is part of a well - directed process,» remarked Anurag Agrawal, Professor at the CSIR - Institute of Genomics and Integrative Biology in Delhi, India, and one of the lead authors of the study.

The biological activity of estrogen and testosterone, the sex hormones of the body, which are believed to play a part in type 2 diabetes development are regulated by a protein known as SHBG (sex hormone - binding globulin).

Not exact matches

By helping to regulate the pace of digestion, protein and fiber also help regulate the break down of starches into sugars and the general passage of carbs through out digestive tract.

When paired with carbohydrates, including protein in a snack will help to keep a turbulent tantrum at bay by regulating the uptake of sugar.

ZenEvo's FIT Chocolate is described as a healthy chocolate and nutrient compound that regulates adiponectin, a protein used by the body to regulate metabolism.

Other «Undisclosed Ingredients» — Because protein powders, like other supplements, are not regulated by the Food and Drug Administration (FDA), unscrupulous manufacturers sometimes sneak ingredients in to the final product that aren't listed on the label.

A protein called peroxisome proliferator — activated receptor g co-activator 1 - alpha (PGC1 - alpha) regulates the expression of many genes identified by the researchers.

«We discovered that Neu1, a protein nicknamed after «neuraminidase 1,» turns the absorption of sugar «on» or «off» in body cells, by regulating the amount of sialic acid on the surface of cells,» Dr. Pshezhetsky explains.

A research group at the University of Basel now describes for the first time a mechanism by which hippocampal neural stem cells regulate their own cell fate via the protein Drosha.

The synaptic vesicle protein that mediates membrane fusion during exocytosis also regulates the rate and extent of this process by controlling vesicle tethering.

Other genes activated by the guide RNA encode mitochondrial proteins that help cells regulate their energy metabolism, and trafficking proteins that are involved in packaging and transporting other proteins.

Other teams are trying to introduce the proteins encoded by the genes directly into cells, while Yamanaka is experimenting with «microRNAs» — snippets of RNA that help regulate gene activity.

«Our work illustrates that this exquisite control mechanism — regulated by PUS7 and pseudouridine — is critical to adjusting the amount of proteins needed for human stem cells to grow and produce blood,» says Cristian Bellodi.

The protein is now known to interact with and control dozens of different genes and proteins, and it helps regulate the cycle of molecular events by which cells grow and reproduce.

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24 - hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA - protein complex of the cell.

This protein is expressed at relatively high levels in proliferating precursors and non-neuronal cells but down - regulated in developing neurons by a brain - enriched regulatory RNA called miR - 9.

A group of LMU physicists led by Professor Erwin Frey, in collaboration with Professor Stefan Diez (Technical University of Dresden and Max Planck Institute for Molecular Cell Biology and Genetics, Dresden), has now developed a model in which the motor proteins that are responsible for the transport of cargo along protofilaments also serve to regulate microtubule lengths.

This hypothesis is supported by the fact that the scientists have identified a genomic region through which BMP protein production is controlled, that is to say, the specific site that regulates the safety circuit triggered when adenomas are detected.

Through a combination of high - resolution cryo - electron microscopy (cryo - EM) and a unique methodology for image analysis, a team of researchers with Berkeley Lab and the University of California (UC) Berkeley has produced an atomic view of microtubules that enabled them to identify the crucial role played by a family of end - binding (EB) proteins in regulating microtubule dynamic instability.

They have also discovered that a protein named Wnt5A promotes metastatic progression, resistance to therapy and poorer prognosis, and one of the ways in which it is regulated is by the anti-aging protein Klotho.

A decade of post-genomic biology has also focused new attention on the regions outside protein - coding genes, many of which are likely to have key functions, through regulating the expression of protein - coding genes and by making a slew of non-coding RNA molecules.

Through their signaling prowess, IDPs help regulate the gas and brake pedals for producing proteins from the DNA code, according to evidence that has accumulated over the past decade, as well as the process by which cells divide.

Blood coagulation is regulated by one set of proteins that causes clotting and another set that prevents it.

Traditional LTP is regulated by the activation of special proteins at synapses called NMDA receptors.

In the past decade or so, researchers have also come to appreciate the key roles played by chromatin proteins and RNA in regulating gene expression.

Using the model organism, Caenorhabditis elegans, the researchers identified over 400 new mRNA editing sites — the majority regulated by ADR - 1 — and declared the protein the first global regulator of RNA editing.

Our team's independent discovery of the ZBTB48 protein is an extension to these recent findings, as we found evidence indicating that cancer cells, in general, are regulated by ZBTB48.

The finding also led them to the protein made by a normal copy of the gene that promotes sleep early in the night and properly regulates sleep cycles.

The researchers found that the blond hair commonly seen in Northern Europeans is caused by a single change in the DNA that regulates the expression of a gene that encodes a protein called KITLG, also known as stem cell factor.

In addition, the total amount of a protein can be regulated by alternative splicing, which is illustrated in the current work by using the general transcription factor TBP (TATA - box binding protein) as an example.

Wyrick and his colleagues also saw less damage around transcription factors, proteins that bind to specific, short stretches of DNA and regulate gene expression by controlling which genes are turned on and off.

Key proteins, produced and regulated by these important genes, activated a cascade of diverse, tissue - specific signals that led to regenerative organ growth.

In fact, the researchers showed that the synthesis of the capsule is controlled by the same mechanisms that regulate the cell cycle, and identified the protein that inhibits the production of the sugar capsule in one of the daughter cells.

By studying the regulation of the clock proteins called Period (PER) and Cryptochrome (CRY)-- proteins that are thought to be involved with metabolism — St. John and Doyle were able to model the mechanisms of two small - molecule drugs — Longdaysin and KL0001 — that regulate the expression of the clock proteins.

Secreted by certain brain cells, APOE is known to regulate cholesterol metabolism within the brain and can bind to A-beta peptides, suggesting that the different forms of the protein may affect whether and how toxic A-beta plaques form.

Proteins can be regulated by a process called ubiquitination, in which an ubiquitin molecule is added to a protein.

These proteins regulate their own expression by building up over a 24 - hour period until they turn their genes off and start the cycle over.

By analyzing skin cells from achromatopsia patients and their unaffected family members, the researchers confirmed that the ATF6 mutations were interfering with the signaling pathway that regulates the unfolded protein response.

These proteins, which are controlled by the metabolic sensor AMP - activated protein kinase, regulate fat production as well as the ability to burn fat.

Based on mouse studies, the researchers suspect that the cone cells of people with achromatopsia are not permanently damaged and could be revived by enhancing the pathway that regulates the unfolded protein response.

New research shows that all - trans - retinoic acid (atRA), the active form of vitamin A, regulates immune system responses in the mouse intestine by controlling expression of the protein HIC1 in cells known as innate lymphoid cells.

As their name suggests, these proteins are regulated by cyclins.

Through mapping proteins that can restrict viral infections, the researchers found a protein called YTHDF2 that can help regulate the human herpes virus 8 by detecting the m6A modification on viral messenger RNA.

However, endocytic waves may be initiated by clathrin through a positive feedback mechanism between clathrin and downstream proteins which includes actin regulating proteins as well as membrane proteins such as PIP3.

They promote the growth of cancerous cells by releasing growth factors and increasing the response of certain proteins that regulate tumor cell development (oncoproteins).

BREATHLESS Nerve endings in the lungs send signals — triggered by force - detecting proteins — to the brain and spinal cord that help regulate breathing.