Here she investigates how cell adhesion to the extracellular matrix
regulates animal development.
Not exact matches
Larsson is at the forefront of merging paleontology and molecular biology in an effort to connect major evolutionary changes — the
development of new species and new characteristics, new shapes and structures, new kinds of
animals — to changes in specific genes and in how those genes are
regulated.
At the same time, as in mice, paternally imprinted genes heavily
regulate placental
development in these
animals.
Molecular analysis showed that heart cells in affected
animals were poorly developed and had mitochondrial defects, indicating that Sap130 - Pcdha9 gene interactions play a crucial role not only in heart
development but also in
regulating metabolic function of the cardiac muscle.
This licensee allows investigators to use materials
regulated by the NRC in research and
development,
animal studies and student training.
In other
animals, those are known to
regulate the
development of neurons and the interactions between them.
The researchers used a technique called RNA interference (RNAi) to screen a group of genes known to be involved in
animal development, in order to study the signaling mechanisms that
regulate whether the
animal would produce a head or tail during regeneration.
My research addresses the chemical
development of the early oceans and atmosphere, the environmental context of early
animal evolution, and the geologic factors that
regulate sedimentary basins.
It is Dr. Fasano's team discovery that «zonulin,» is the molecule which
regulates intestinal permeability (also known as «leaky gut») and their totally ground - breaking research that linked an overproduction of zonulin (gluten is a clear known trigger for such in celiacs) to the
development of a series of autoimmune diseases, including Type 1 diabetes, celiac disease and multiple sclerosis (at least in
animals at this point in time).
Animal and clinical studies indicate that the AR signaling pathway is required for appropriate
development of skeletal muscles, since it
regulates increases in lean muscle mass, muscle strength, and muscle protein synthesis.
In humans, both the HPA system and the autonomic nervous system show developmental changes in infancy, with the HPA axis becoming organized between 2 and 6 months of age and the autonomic nervous system demonstrating relative stability by 6 to 12 months of age.63 The HPA axis in particular has been shown to be highly responsive to child - caregiver interactions, with sensitive caregiving programming the HPA axis to become an effective physiological regulator of stress and insensitive caregiving promoting hyperreactive or hyporeactive HPA systems.17 Several
animal models as well as human studies also support the connection between caregiver experiences in early postnatal life and alterations of autonomic nervous system balance.63 - 65 Furthermore, children who have a history of sensitive caregiving are more likely to demonstrate optimal affective and behavioral strategies for coping with stress.66, 67 Therefore, children with histories of supportive, sensitive caregiving in early
development may be better able to self -
regulate their physiological, affective, and behavioral responses to environmental stressors and, consequently, less likely to manifest disturbed HPA and autonomic reactivity that put them at risk for stress - related illnesses such as asthma.