Sentences with phrase «regulates endothelial cell»

The ability to up - regulate endothelial cell adhesion molecules after exposure to cytokines was unaffected by repeated subculturing of cells, because we noted identical staining patterns for passage 30 cells (we did attempt to extend this observation to include later passage cells).

The resulting endothelial cell lines described in this study retain their phenotype after repeated passage, require minimal nutritional support and, importantly, may be useful for identifying factors that regulate endothelial cell proliferation and tumor cell adhesion in different anatomical regions.

FoxOs are lineage - restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

In other major projects in the laboratory, we investigate the molecular mechanisms that regulate endothelial cell polarization and movement, a critical and initiating event in the formation of new blood vessels and in repair of injured vessels.

Not exact matches

The blood - brain barrier is a layer of tightly packed endothelial cells and connective cells called astrocytes that strictly regulates the flow of chemicals in and out of the brain.

Instead of dispensing ink, Organovo's bioprinter uses two robotic tips to deposit globs of cells — in this case, endothelial cells that line blood - vessel walls, smooth muscle cells that regulate vessel dilation and contraction, and structural fibroblast cells.

When primary cultures from these mice are stimulated with proinflammatory cytokines, the endothelial cell fraction responds by up - regulating the inducible endothelial cell adhesion molecules, E-selectin and VCAM - 1.

The immortalized endothelial cell lines established from H - 2Kb - tsA58 mice provide, for the first time, a cell culture system to examine factors regulating angiogenesis and tumor cell arrest in different organ systems.

MicroRNA - 195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1.

MicroRNA - 24 inhibits the proliferation and migration of endothelial cells in patients with atherosclerosis by targeting importin - a3 and regulating inflammatory responses.

HIF - 2α expression regulates sprout formation into 3D fibrin matrices in prolonged hypoxia in human microvascular endothelial cells.

Syk and Src Family Kinases Regulate C - type Lectin Receptor 2 (CLEC - 2)- mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells.

Endothelial cell specific adhesion molecule (ESAM) localizes to platelet — platelet contacts and regulates thrombus formation in vivo.

Anastellin, a fragment of the first type III repeat of fibronectin, inhibits extracellular signal - regulated kinase and causes G1 arrest in human microvessel endothelial cells.

Endothelial cells line the inside of all blood vessels and regulate inflammation, blood clotting following injury and blood pressure levels.

Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone / salt - mediated cardiac remodeling and vascular reactivity but not blood pressure

«Our findings show for the first time that (the enzyme) regulates endothelial filopodia formation and, most importantly, endothelial cell migration by rearranging the cells» phospholipid composition,» the authors report.

Recent studies have reported that GLP - 1 improves the function of renal endothelial cells (which regulate blood clotting, immune response and blood vessel activity, among other critical functions, and are impaired by insulin resistance) and can prevent some renal pathologies in diabetic rodents.