Sentences with phrase «regulates tumor microenvironment»
Our novel data show that adenosine generated by MCs regulates tumor microenvironment by decreasing fibroblast responses to TGFβ acting through A2 adenosine receptors.
http://www.vicc.org/ Not exact matches
Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment?
Jimenez - Garcia L, Herranz S, Higueras MA, Luque A, Hortelano S. Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarizaTumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarizatumor growth through modulation of macrophage polarization.
Research in the Immunology, Microenvironment and Metastasis program is aimed at 1) merging basic mechanistic understanding of multidisciplinary pathways of host - tumor interactions and metastatic dissemination with novel translational opportunities for diseases diagnosis and immunotherapy, as well as 2) investigating mechanisms regulating immune responses in cancer and their potential therapeutic manipulation.
We report that ABL kinases promoted metastasis of breast cancer cells to bone by regulating the crosstalk between tumor cells and the bone microenvironment.