Sentences with phrase «regulates tumorigenesis»
His research program is interested in understanding how cellular metabolism regulates tumorigenesis.
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«This study demonstrates the significance of mammalian iRhoms in regulating an EGFR signaling event that promotes accelerated wound healing and triggers tumorigenesis,» Shultz says.
Moreover; the PI3K / AKT pathway also can contribute to melanoma tumorigenesis through mutations or loss in PTEN and dysregulation in expression of AKT, which positively regulates the G1 / S phase progression in cell cycle, suppresses apoptosis and promotes cellular survival.
There are also other drivers which regulate melanoma tumorigenesis.
Cancer studies have increasingly focused on chromatin — the intertwined proteins and DNA that are packaged into chromosomes — because of its ability to regulate genes important for either activating or inhibiting tumorigenesis.