Sentences with phrase «regulating animal aging»

The role of insulin / IGF signaling in regulating animal aging is therefore evolutionarily conserved.

Not exact matches

«This aging system that we know about in the worm is out there in other animals, regulating their aging.

p53 also plays important and complex roles in regulating cellular senescence and animal aging, and can exert both pro-aging and pro-longevity effects in mice.

In fact, because many mechanisms of aging are broadly conserved across animals, including Drosophila, research on the signaling networks that regulate this process could eventually have profound impacts on the treatment of age - related diseases like Alzheimer's.

In the US, the Centers for Disease Control and Prevention (CDC) regulates importations of dogs and cats and these animals should not be imported from rabies - endemic countries until one month after they receive their rabies vaccination (given at 3 months of age).

Age can also be a factor in an animal's tendency to overheat — very young animals may not have a fully developed temperature regulating system, and older pets» organ systems may not be functioning at 100 percent, leaving them prone to heat - related damage.

Hormones regulate the change from fuzzy puppy coats to the adult version, and they have an affect again as the animal ages, often causing hair to become thinner with a dryer texture.

In humans, both the HPA system and the autonomic nervous system show developmental changes in infancy, with the HPA axis becoming organized between 2 and 6 months of age and the autonomic nervous system demonstrating relative stability by 6 to 12 months of age.63 The HPA axis in particular has been shown to be highly responsive to child - caregiver interactions, with sensitive caregiving programming the HPA axis to become an effective physiological regulator of stress and insensitive caregiving promoting hyperreactive or hyporeactive HPA systems.17 Several animal models as well as human studies also support the connection between caregiver experiences in early postnatal life and alterations of autonomic nervous system balance.63 - 65 Furthermore, children who have a history of sensitive caregiving are more likely to demonstrate optimal affective and behavioral strategies for coping with stress.66, 67 Therefore, children with histories of supportive, sensitive caregiving in early development may be better able to self - regulate their physiological, affective, and behavioral responses to environmental stressors and, consequently, less likely to manifest disturbed HPA and autonomic reactivity that put them at risk for stress - related illnesses such as asthma.