Sentences with phrase «regulating cell life»

«Because of the important role of UPR in regulating cell life / death decisions, it is critical that mechanisms are in place to prevent unnecessary UPR activation in response to innocuous or low - level stimuli,» said Wilkinson.

Not exact matches

What guides the process in all living things is DNA, which regulates every cell of every plant and animal.

Jordan happened to be the favorite player of research fellow Steve Miller, the discoverer of the gene family whose leaps enabled Miller and biologist David Kirk to isolate four genes in the algae Volvox that regulate aspects of cell life.

This degenerative buildup means that the length of our lives is regulated by the balance between how fast new damage strikes our cells and how efficiently this damage is corrected.

In cancer, these switches inappropriately activate or silence important genes, such as those that regulate cell growth and life cycle, ultimately leading to tumors.

The new discovery, reported Aug. 31 in the journal Cell by King's lab and the lab of Jon Clardy at Harvard Medical School, suggests that choanos «eavesdrop» on bacteria to make sense of their environment and regulate their life history.

In their efforts to conquer the aging process, researchers are zeroing in on one specific part of the cell: mitochondria, the energy - generating organelles that control our metabolism and, it seems, help regulate how long we live.

Changes in cellular metabolites have been shown to regulate embryonic stem cell development at the earliest stages of life.

Researcher Scott Soleimanpour, M.D., who lives with type 1 diabetes, publishes findings about faulty cell recycling that disrupts the ability of beta cells to regulate blood sugar.

In collaboration with the team of Eduard Sabidó at the Proteomics Unit of the Centre for Genomic Regulation and Universitat Pompeu Fabra, the researchers analyzed the proteins in Capsaspora to determine how the organism might be regulating its internal cell processes at different life stages.

In contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cycle.

Working copies of active genes — called messenger RNAs or mRNAs — are positioned strategically throughout living tissues, and their location often helps regulate how cells and tissues grow and develop.

In self - renewing tissues, such as the skin, chromatin modification is also involved in regulating the replacement of old or damaged cells in later stages in life.

«This may be the primordial gene that regulates nutrient sensing and helps an animal overcome stressful conditions — and helps an animal live a long time through dietary - restriction conditions,» says the study's senior author, Andrew Dillin, an associate professor of molecular and cell biology at the Salk Institute in La Jolla, Calif..

Protein kinases, most scientists would agree, regulate nearly every aspect of cell life.

If you want to control the processes inside living cells, you have to confront the gatekeepers — the molecular pumps, pores and channels that regulate the transport of particles in and out of a cell.

In medicine, the Institute's goal is to advance the science and engineering necessary to develop biomimetic materials, microdevices, microrobots, and innovative disease reprogramming technologies that emulate how living cells, tissues and organs self - organize and naturally regulate themselves.

Living cells are surrounded by a membrane that tightly regulates what gets in and out of the cell.

Fetal tissue is treated as the mother's tissue, and is governed by the consent provisions of the Human Tissue Act which regulates the storage and use of tissues and cells from living donors.

In all living organisms, the cell cycle must be tightly regulated to ensure that new cells are created only when necessary and have an accurate copy of DNA to function normally.

Increasing the expression of PGRP - SC, the molecules that regulate the immune response to bacteria in the intestinal epithelium (a response that can be mimicked by drugs), restored microbial balance and halted overproiferation of stem cells, increasing life span.

Kinetics of regulated protein - protein interactions revealed with firefly luciferase complementation imaging in cells and living animals

All living cells, from simple yeasts to human brain cells, regulate their rate of growth and their ultimate size and shape.

In August 2001, she joined the Imaging Facility Group at the Laboratory of Receptor Biology and Gene Expression (LRBGE) at the National Institutes of Health as a Postdoctoral Fellow to investigate the glucocorticoid receptor (GR) dynamics at promoter elements in live cells and the GR - regulated pol II transcription.

Agre shared the Nobel Prize in Chemistry with Roderick MacKinnon in 2003 for his discovery of aquaporins — channels that regulate and facilitate water molecule transport through cell membranes, a process essential to all living organisms.

Utilizing sophisticated genetically engineered mouse models, we will study how these conserved longevity pathways regulate the homeostasis and aging of adult stem cells, including hematopoietic stem cells, the adult stem cells that sustain all blood lineages throughout life.

Essential for life, the hormone insulin regulates many metabolic processes that provide cells with needed energy.

Salt is also an absolutely essential part of both human and animal life due to the sodium that is contains, which is used to maintain some of the body's most integral functions including regulating fluid in blood cells and helping to send information to nerves and muscles.

Phosphorus, which is one of the major building blocks of life, makes up a portion of your DNA and cell membranes, helps regulate protein activity in your cells, and also contributes to your bone and tooth tissue.

Iodine is an essential trace mineral needed for the body's production of thyroid hormones, which regulate metabolism — the chemical reactions that occur in every cell in the body and provide energy for life.