The research centre currently consists of seven groups studying epigenetic mechanisms
regulating cellular differentiation programs.
Not exact matches
The authors uncover the
cellular and molecular mechanisms, as well as the gene network
regulated by Sox9 during the early steps of skin tumor initiation and demonstrates that Sox9 controls the long term maintenance and expansion of oncogene expressing cells by promoting self - renewing division and inhibiting
differentiation.
Wnt / beta - catenin signaling is a tightly
regulated, multi-functional pathway involved in in many
cellular processes, including
cellular decisions about proliferation versus
differentiation.
Manuscripts typical of this section would describe experiments generating and analyzing lists of genes and studies of how those genes combine to
regulate:
differentiation of a particular cell type;
cellular, tissue, or organ response to toxic / pathogenic agents; adaptation to environmental stresses.