Sentences with phrase «regulating cellular senescence»
p53 also plays important and complex roles in regulating cellular senescence and animal aging, and can exert both pro-aging and pro-longevity effects in mice.
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They focused in on genes known to regulate a cellular state called senescence.
Busulfan selectively induces cellular senescence but not apoptosis in WI38 fibroblasts via a p53 - independent but extracellular signal - regulated kinase - p38 mitogen - activated protein kinase - dependent mechanism.
The ability to measure the degree of cellular senescence is important in understanding the biological processes regulating cell aging and immortalization.