Sentences with phrase «regulating epithelial»

MBI scientists have discovered a feedback mechanism that regulates epithelial tube contractility in a living organism, the C. elegans nematode worm.

Interaction between FIP5 and SNX18 regulates epithelial lumen formation.

[46] Among the roles of cytokines in breast cancer is their ability to regulate epithelial - mesenchymal transitions (EMT) and drug resistance.

Not exact matches

In subsequent experiments, the Einstein team deciphered other parts of the Rac1 signaling cascade during invasion and showed that this signaling mechanism is regulated differently in normal breast epithelial cells.

In a previous study, Professor Schmidt - Ott and his team discovered that it regulates the differentiation of epithelial cells — they line the cavities and surfaces of structures throughout the body — in the mouse embryo.

Further analysis revealed that overexpression of these lncRNAs in turn changed the expression of proteins that regulate a well - known developmental process, termed the epithelial - to - mesenchymal transition (EMT).

In the study, the protein Miro1 was shown to regulate the transfer of mitochondria from mesenchymal stem cells to epithelial cells.

According to Dr. Bleich and his co-investigators, «Epithelial barrier function is predominantly dependent on tight junction proteins, which regulate transport into and between cells.

It may also represent a universal mechanism that regulates contractility in other epithelial tubes, including those found throughout our bodies.

Collectively, these results suggest that Nrk negatively regulates the estrogen - dependent proliferation of mammary epithelial cells, the disruption of which leads to breast tumors.

MicroRNA -7-5p regulates the proliferation and migration of intestinal epithelial cells by targeting trefoil factor 3 via inhibiting the phosphoinositide 3 - kinase / Akt signalling pathway.

CEBPG regulates ERCC5 / XPG expression in human bronchial epithelial cells and this regulation is modified by E2F1 / YY1 interactions.

Matthews» laboratory research, with long - term support from the National Institutes of Health, focuses on the fundamental mechanisms used by epithelial tissues to regulate salt secretion — which goes awry in several diseases, including cystic fibrosis and many forms of diarrhea.

Large - scale genomic studies have shown that half of epithelial ovarian cancers (EOCs) have alterations in genes regulating homologous recombination (HR) repair.

Assembly of connexin43 into gap junctions is regulated differentially by E-cadherin and N - cadherin in rat liver epithelial cells.

Rab11b regulates the trafficking and recycling of the epithelial sodium channel (ENaC).

Adherence of H. pylori to gastric epithelial cells is critical for induction of inflammation and injury; therefore, the overarching theme for our research has been delineation of the molecular signaling events initiated by bacterial: epithelial cell contact that regulate phenotypes related to carcinogenesis.

Characterising the hierarchy of mammary epithelial cells (MECs) and how they are regulated during adult development is important for understanding how breast cancer arises.

In the small intestine, gluten triggers the release of zonulin, a protein that regulates the tight junctions between epithelial cells and therefore intestinal, but also blood - brain barrier function.

Estradiol - regulated transamidation of keratins by vaginal epithelial cell transglutaminase.

They also serve as the major energy source for colonocytes (epithelial cells of the colon) and are thought to regulate human gene expression in order to reduce the risk of gastrointestinal disorders, some forms of cancer, and cardiovascular disease.