Specifically, the team hypothesizes that microRNA miR - 24 is a key regulator of actin cytoskeleton dynamics (i.e. the inner structural support of a cell); therefore, it plays a critical role in
regulating multiple disease processes, including the angiogenesis (blood vessel growth), inflammation, and fibrosis (thickening and scarring of tissue) associated with choroidal neovascularization (CNV) in wet AMD.
Not exact matches
As published this week in Nucleic Acids Research, they have discovered a mechanism that
regulates the expression of alpha - synuclein, a protein linked to Parkinson's
disease and
multiple system atrophy (MSA).
Prior research has shown that macrophage migration inhibitory factor (MIF)-- a protein that helps
regulate immune and inflammatory reactions — is elevated in people with autoimmune
diseases like
multiple sclerosis and colitis.
According to studies, curcumin ameliorates psoriasis, inflammatory bowel
disease, and
multiple sclerosis by inhibiting
regulating inflammatory cytokines.
It is Dr. Fasano's team discovery that «zonulin,» is the molecule which
regulates intestinal permeability (also known as «leaky gut») and their totally ground - breaking research that linked an overproduction of zonulin (gluten is a clear known trigger for such in celiacs) to the development of a series of autoimmune
diseases, including Type 1 diabetes, celiac
disease and
multiple sclerosis (at least in animals at this point in time).
For instance, genetic
diseases may be recessive, which means that both parents must contribute a gene for the
disease to be expressed, or
regulated by
multiple genes that may even be located on different chromosomes, or even triggered by environmental factors.