In addition to the propeptide, other binding proteins are capable of
regulating myostatin activity in vitro, including follistatin [19], [21], FLRG [22], and Gasp - 1 [23].
It regulates myostatin - signaling pathways, leading to lower action of myostatin inhibition that results in more muscle fiber building.
Not exact matches
The new therapy is based on a protein called
myostatin, which normally
regulates muscle growth.
Because I was unable to examine the effect of overexpressing FLRG in the complete absence of
myostatin, it was difficult to ascertain the relative importance of these additional ligands compared to
myostatin in
regulating muscle mass.
According to this model, local control of muscle growth would be achieved by
regulating the extent to which the latent form of
myostatin is activated at the target site, whereas global control of the metabolic homeostatic balance between muscle and other tissues would be achieved by
regulating the size of the circulating pool of
myostatin.
Myostatin, a member of the TGFβ superfamily of growth factors that is expressed primarily in skeletal muscle cells, is a genetically validated target that
regulates muscle mass.
• SRK - 015 specifically targets the activation of latent forms of
myostatin and does not inhibit GDF11 or Activin A, proteins that are structurally similar to
myostatin but implicated in
regulating a wide range of biological processes beyond muscle biology.
Anyway, there are a few studies that have found that a compound in this Cystoseira marine algae, called «sulfated polysaccharides» binds to and
regulates the bioactivity of
myostatin.2 Wow, doesn't that sound great?