Sentences with phrase «regulating signal transduction»

This work revealed new roles for XBP - 1 in regulating signal transduction through the B cell receptor; in regulating the expression of important transcription factors in B cells; in maintaining proper lipid synthesis and protein glycosylation in B cells; and in colonization of stimulated B cells into the bone marrow for sustention of antibody production.

They regulate signal transduction and indirectly control plant defense mechanisms.

Not exact matches

My postdoctoral work involved signal transduction pathways that regulate chemotaxis.

A well - known class of proteins may fill in the dotted lines that connect signal transduction pathways to the genes they regulate.

These data indicate that DGKζ and Cbl - b differentially regulate TCR signal transduction.

Given the predominant role for DAG on regulating Ras / Erk and PKC - θ signaling and Cbl - b for regulating PI (3) K signaling, we hypothesized that T cells deficient in DGKζ or Cbl - b would alter TCR signal transduction through distinct mechanisms, such that DGKζ - deficient T cells would demonstrate strongly enhanced Ras / ERK activation, but only modestly enhanced NF - κB activation, and Cbl - b — deficient T cells would demonstrate modestly enhanced Ras / ERK activation and strongly enhanced NF - κB activation.

We study the signal transduction pathways regulating cell growth and proliferation, with an emphasis on kinase enzymes.

Countering the prevailing theory that cellular hydrogen peroxide signaling is broad and non-specific, Whitehead Institute scientists have discovered that this reactive oxygen species (ROS) in fact triggers a distinct signal transduction cascade under control of the mitochondrial respiratory chain — the Syk pathway — that regulates transcription, translation, metabolism, and the cell cycle in diverse cell types.

One mechanism could be to differentially regulate the molecular components involved in cue detection, such as ORs or VRs [20] or in known elements of their signal transduction pathways, under the control of sex - specific hormones.

Sethna F, Zhang M, Kaphzan H, Klann E, Autio D, Cox CL, Wang H. (2016) Calmodulin activity regulates group I metabotropic glutamate receptor - mediated signal transduction and synaptic depression.

Simplet / Fam53b is required for Wnt signal transduction by regulating β - catenin nuclear localization.