Sentences with phrase «regulators of gene activity»

The team found that humans are equipped with tiny differences in a particular regulator of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.

Because the prion - forming protein identified in the study normally functions as a regulator of gene activity, the researchers say their discovery raises the possibility that when it switches to a prion state, it could alter genetic expression and bacterial behavior.

Niakan's group focused on a gene called OCT4 (also known as POU5F1), a master regulator of gene activity, which is important in mouse embryo development.

Not exact matches

Igoshin said that when the researchers set out to find how sporulation decisions were timed to the cell cycle, several studies including prior work by team members, provided a significant clue: Under starvation conditions, the activity of the master regulator gene had been shown to spike once per cell cycle.

«This tells us that the NuRD complex is very influential — not only does it affect the activity of genes directly, it also controls other regulators of multiple genes,» Bonni said.

Researchers also found that levels of cAMP and pCREB, possible upstream regulators of some circadian genes, were correlated with locomotor activity.

Tet2 is a type of cellular enzyme known as an epigenetic regulator — responsible for making specific chemical annotations to regions of DNA that alter the activity of many different genes.

The researchers found that the ability to control gene activity allows Ikaros to act as a master regulator of the function of blood cells.

Gene ontology (GO) analysis of genes within 250 kb of a PORE sequence revealed enrichment in processes such as transcription regulator activity (p < 0.001), sex determination (p < 0.005), insulin receptor signaling (p < 0.001), development (p < 0.0005), and protein phosphorylation (p < 0.005).

Chromatin folding is increasingly recognized as a regulator of genomic processes such as gene activity.